SCOP 1.75: Domain d2o6ge1: 2o6g E:3-112

Lineage for d2o6ge1 (2o6g E:3-112)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (84 families)
   contains a small beta-sheet (wing)

5. Family a.4.5.23: Interferon regulatory factor [46877] (3 proteins)
   Pfam PF00605

6. Protein Interferon regulatory factor 3, IRF-3 [116791] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [116792] (3 PDB entries)
   Uniprot Q14653 3-112

8. Domain d2o6ge1: 2o6g E:3-112 [148628]
   automatically matched to d1t2ka_

Details for d2o6ge1

PDB Entry: 2o6g, 3.1 Å

PDB Description: crystal structure of irf-3 bound to the interferon-b enhancer

PDB Compounds: (E:) Interferon regulatory factor 3

SCOP Domain Sequences for d2o6ge1:

Sequence; same for both SEQRES and ATOM records:

>d2o6ge1 a.4.5.23 (E:3-112) Interferon regulatory factor 3, IRF-3 {Human (Homo sapiens) [TaxId: 9606]}
tpkprilpwlvsqldlgqlegvawvnksrtrfripwkhglrqdaqqedfgifqawaeatg
ayvpgrdkpdlptwkrnfrsalnrkeglrlaedrskdphdphkiyefvns

Timeline for d2o6ge1:

• d2o6ge1 is new in SCOP 1.75
  
• d2o6ge1 appears in SCOPe 2.01
  
• d2o6ge1 appears in the current release, SCOPe 2.08, called d2o6ge_