SCOP 1.75: Domain d2nn6e1: 2nn6 E:5-191

Lineage for d2nn6e1 (2nn6 E:5-191)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.14: Ribosomal protein S5 domain 2-like [54210] (1 superfamily)
   core: beta(3)-alpha-beta-alpha; 2 layers: alpha/beta; left-handed crossover

4. Superfamily d.14.1: Ribosomal protein S5 domain 2-like [54211] (12 families)

5. Family d.14.1.4: Ribonuclease PH domain 1-like [54229] (10 proteins)

6. Protein Exosome complex exonuclease RRP42 [159908] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [159909] (1 PDB entry)
   Uniprot Q15024 5-191

8. Domain d2nn6e1: 2nn6 E:5-191 [148303]
   Other proteins in same PDB: d2nn6a1, d2nn6a2, d2nn6b1, d2nn6b2, d2nn6c1, d2nn6c2, d2nn6d1, d2nn6d2, d2nn6e2, d2nn6f1, d2nn6f2, d2nn6g1, d2nn6g2, d2nn6g3, d2nn6h1, d2nn6h2, d2nn6h3, d2nn6i1, d2nn6i2
   mutant

Details for d2nn6e1

PDB Entry: 2nn6, 3.35 Å

PDB Description: Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4, and Rrp40

PDB Compounds: (E:) Exosome complex exonuclease RRP42

SCOP Domain Sequences for d2nn6e1:

Sequence, based on SEQRES records:

>d2nn6e1 d.14.1.4 (E:5-191) Exosome complex exonuclease RRP42 {Human (Homo sapiens) [TaxId: 9606]}
tlseaekvyivhgvqedlrvdgrgcedyrcvevetdvvsntsgsarvklghtdilvgvka
emgtpklekpnegyleffvdcsasatpefegrggddlgteiantlyrifnnkssvdlktl
cisprehcwvlyvdvlllecggnlfdaisiavkaalfntriprvrvledeegskdielsd
dpydcir

Sequence, based on observed residues (ATOM records):

>d2nn6e1 d.14.1.4 (E:5-191) Exosome complex exonuclease RRP42 {Human (Homo sapiens) [TaxId: 9606]}
tlseaekvyivhgvqedlrvdgrgcedyrcvevetdvvsntsgsarvklghtdilvgvka
emgtpklekpnegyleffvdcsasatpefegrggddlgteiantlyrifnnkssvdlktl
cisprehcwvlyvdvlllecggnlfdaisiavkaalfntriprvrvledielsddpydci
r

Timeline for d2nn6e1:

• d2nn6e1 is new in SCOP 1.75
  
• d2nn6e1 appears in SCOPe 2.01
  
• d2nn6e1 appears in the current release, SCOPe 2.08