SCOPe 2.07: Domain d2nn6a2: 2nn6 A:185-302

Lineage for d2nn6a2 (2nn6 A:185-302)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.101: Ribonuclease PH domain 2-like [55665] (1 superfamily)
   beta(2)-alpha-beta(2)-alpha; 3 layers: alpha/beta/alpha; antiparallel sheet: order 2134

4. Superfamily d.101.1: Ribonuclease PH domain 2-like [55666] (2 families)

5. Family d.101.1.1: Ribonuclease PH domain 2-like [55667] (11 proteins)

6. Protein Exosome complex exonuclease RRP45 [160586] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [160587] (1 PDB entry)
   Uniprot Q86Y41 185-302

8. Domain d2nn6a2: 2nn6 A:185-302 [148296]
   Other proteins in same PDB: d2nn6a1, d2nn6b1, d2nn6b2, d2nn6c1, d2nn6c2, d2nn6d1, d2nn6d2, d2nn6e1, d2nn6e2, d2nn6f1, d2nn6f2, d2nn6g1, d2nn6g2, d2nn6g3, d2nn6h1, d2nn6h2, d2nn6h3, d2nn6i1, d2nn6i2
   protein/RNA complex

Details for d2nn6a2

PDB Entry: 2nn6, 3.35 Å

PDB Description: Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4, and Rrp40

PDB Compounds: (A:) Polymyositis/scleroderma autoantigen 1

SCOPe Domain Sequences for d2nn6a2:

Sequence; same for both SEQRES and ATOM records:

>d2nn6a2 d.101.1.1 (A:185-302) Exosome complex exonuclease RRP45 {Human (Homo sapiens) [TaxId: 9606]}
lsihhmpicvsfaffqqgtyllvdpnereervmdgllviamnkhreictiqssggimllk
dqvlrcskiagvkvaeitelilkalendqkvrkeggkfgfaesianqritafkmekap

Timeline for d2nn6a2:

• d2nn6a2 first appeared in SCOP 1.75
  
• d2nn6a2 appears in SCOPe 2.06
  
• d2nn6a2 appears in the current release, SCOPe 2.08