SCOPe 2.08: Domain d2j4gb2: 2j4g B:127-436

Lineage for d2j4gb2 (2j4g B:127-436)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (15 families)

5. Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain [82253] (4 proteins)
   Glycosyl hydrolase family 67, GH67; structurally related to GH20; contains extra C-terminal alpha-helical subdomain

6. Protein Glucosaminidase GH84, catalytic domain [141790] (1 species)

7. Species Bacteroides thetaiotaomicron [TaxId:818] [141791] (8 PDB entries)
   Uniprot Q89ZI2 148-457

8. Domain d2j4gb2: 2j4g B:127-436 [147880]
   Other proteins in same PDB: d2j4ga1, d2j4ga3, d2j4gb1, d2j4gb3
   automated match to d2j4ga2
   complexed with act, gol, nb1

Details for d2j4gb2

PDB Entry: 2j4g, 2.25 Å

PDB Description: bacteroides thetaiotaomicron gh84 o-glcnacase in complex with n-butyl-thiazoline inhibitor

PDB Compounds: (B:) Hyaluronoglucosaminidase

SCOPe Domain Sequences for d2j4gb2:

Sequence, based on SEQRES records:

>d2j4gb2 c.1.8.10 (B:127-436) Glucosaminidase GH84, catalytic domain {Bacteroides thetaiotaomicron [TaxId: 818]}
vryrgvvegfygtpwshqarlsqlkfygknkmntyiygpkddpyhsapnwrlpypdkeaa
qlqelvavanenevdfvwaihpgqdikwnkedrdlllakfekmyqlgvrsfavffddisg
egtnpqkqaellnyidekfaqvkpdinqlvmcpteynkswsnpngnylttlgdklnpsiq
imwtgdrvisditrdgiswinerikrpayiwwnfpvsdyvrdhlllgpvygndttiakem
sgfvtnpmehaesskiaiysvasyawnpakydtwqtwkdairtilpsaaeelecfamhns
dlgpnghgyr

Sequence, based on observed residues (ATOM records):

>d2j4gb2 c.1.8.10 (B:127-436) Glucosaminidase GH84, catalytic domain {Bacteroides thetaiotaomicron [TaxId: 818]}
vryrgvvegfygtpwshqarlsqlkfygknkmntyiygpkddpyhsapnwrlpypdkeaa
qlqelvavanenevdfvwaihpgqdikwnkedrdlllakfekmyqlgvrsfavffddisg
egtnpqkqaellnyidekfaqvkpdinqlvmcpteynkswspngnylttlgdklnpsiqi
mwtgdrvisditrdgiswinerikrpayiwwnfpvsdyvrdhlllgpvygndttiakems
gfvtnpmehaesskiaiysvasyawnpakydtwqtwkdairtilpsaaeelecfamhnsd
lgpnghgyr

Timeline for d2j4gb2:

• d2j4gb2 first appeared in SCOP 1.75
  
• d2j4gb2 appears in SCOPe 2.07