SCOPe 2.08: Domain d2hypa1: 2hyp A:10-265

Lineage for d2hypa1 (2hyp A:10-265)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.159: Metallo-dependent phosphatases [56299] (1 superfamily)
   4 layers: alpha/beta/beta/alpha; mixed beta sheets; contains duplication

4. Superfamily d.159.1: Metallo-dependent phosphatases [56300] (13 families)
   different families of this superfamily are groupped in a single Pfam family, Pfam PF00149

5. Family d.159.1.11: GpdQ-like [160875] (2 proteins)
   part of Pfam PF00149

6. Protein Rv0805 cyclic nucleotide phosphodiesterase [160876] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [160877] (3 PDB entries)
   Uniprot O06629 10-265

8. Domain d2hypa1: 2hyp A:10-265 [147459]
   complexed with br, cac, fe, mn; mutant

Details for d2hypa1

PDB Entry: 2hyp, 2.05 Å

PDB Description: crystal structure of rv0805 d66a mutant

PDB Compounds: (A:) Hypothetical protein RV0805

SCOPe Domain Sequences for d2hypa1:

Sequence, based on SEQRES records:

>d2hypa1 d.159.1.11 (A:10-265) Rv0805 cyclic nucleotide phosphodiesterase {Mycobacterium tuberculosis [TaxId: 1773]}
prpdyvllhisdthliggdrrlygavdaddrlgelleqlnqsglrpdaivftgdlaakge
paayrklrglvepfaaqlgaelvwvmgnhddraelrkflldeapsmapldrvcmidglri
ivldtsvpghhhgeirasqlgwlaeelatpapdgtilalhhppipsvldmavtvelrdqa
algrvlrgtdvrailaghlhystnatfvgipvsvasatcytqdltvaaggtrgrdgaqgc
nlvhvypdtvvhsvip

Sequence, based on observed residues (ATOM records):

>d2hypa1 d.159.1.11 (A:10-265) Rv0805 cyclic nucleotide phosphodiesterase {Mycobacterium tuberculosis [TaxId: 1773]}
prpdyvllhisdthliggddaddrlgelleqlnqsglrpdaivftgdlaakgepaayrkl
rglvepfaaqlgaelvwvmgnhddraelrkflldeapsmapldrvcmidglriivldtsv
pghhhgeirasqlgwlaeelatpapdgtilalhhppipsvldmavtvelrdqaalgrvlr
gtdvrailaghlhystnatfvgipvsvasatcgcnlvhvypdtvvhsvip

Timeline for d2hypa1:

• d2hypa1 first appeared in SCOP 1.75
  
• d2hypa1 appears in SCOPe 2.07