Lineage for d2hwzl2 (2hwz L:107-213)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2745637Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
  6. 2748802Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)
  7. 2748803Species Human (Homo sapiens) [TaxId:9606] [88569] (147 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody
  8. 2748816Domain d2hwzl2: 2hwz L:107-213 [147430]
    Other proteins in same PDB: d2hwzl1
    automatically matched to d1dqdl2

Details for d2hwzl2

PDB Entry: 2hwz (more details), 1.8 Å

PDB Description: fab fragment of humanized anti-viral antibody medi-493 (synagis tm)
PDB Compounds: (L:) Immunoglobulin Fab light chain

SCOPe Domain Sequences for d2hwzl2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2hwzl2 b.1.1.2 (L:107-213) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

SCOPe Domain Coordinates for d2hwzl2:

Click to download the PDB-style file with coordinates for d2hwzl2.
(The format of our PDB-style files is described here.)

Timeline for d2hwzl2: