Lineage for d2h8ha2 (2h8h A:141-246)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1424633Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flaked by two helices
  4. 1424634Superfamily d.93.1: SH2 domain [55550] (2 families) (S)
  5. 1424635Family d.93.1.1: SH2 domain [55551] (35 proteins)
    Pfam PF00017
  6. 1424652Protein c-src tyrosine kinase [55556] (3 species)
  7. 1424659Species Human (Homo sapiens) [TaxId:9606] [55557] (45 PDB entries)
  8. 1424708Domain d2h8ha2: 2h8h A:141-246 [147241]
    Other proteins in same PDB: d2h8ha1, d2h8ha3
    automatically matched to d1hcsb_
    complexed with h8h

Details for d2h8ha2

PDB Entry: 2h8h (more details), 2.2 Å

PDB Description: src kinase in complex with a quinazoline inhibitor
PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d2h8ha2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2h8ha2 d.93.1.1 (A:141-246) c-src tyrosine kinase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2h8ha2:

Click to download the PDB-style file with coordinates for d2h8ha2.
(The format of our PDB-style files is described here.)

Timeline for d2h8ha2: