SCOPe 2.05: Domain d2grrb_: 2grr B:

Lineage for d2grrb_ (2grr B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.12: Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain [69099] (1 family)
   automatically mapped to Pfam PF07834

5. Family a.118.12.1: Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain [69100] (2 proteins)

6. Protein Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain [69101] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [158788] (9 PDB entries)
   Uniprot P46060 431-587! Uniprot P46060 432-587

8. Domain d2grrb_: 2grr B: [147168]
   Other proteins in same PDB: d2grra_
   automated match to d1kpsb_

Details for d2grrb_

PDB Entry: 2grr, 1.3 Å

PDB Description: crystal structure of human rangap1-ubc9-d127s

PDB Compounds: (B:) ran gtpase-activating protein 1

SCOPe Domain Sequences for d2grrb_:

Sequence; same for both SEQRES and ATOM records:

>d2grrb_ a.118.12.1 (B:) Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
padvstflafpspekllrlgpkssvliaqqtdtsdpekvvsaflkvssvfkdeatvrmav
qdavdalmqkafnsssfnsntfltrllvhmgllksedkvkaianlygplmalnhmvqqdy
fpkalaplllafvtkpnsalescsfarhsllqtlykv

Timeline for d2grrb_:

• d2grrb_ first appeared in SCOP 1.75, called d2grrb1
  
• d2grrb_ appears in SCOPe 2.04
  
• d2grrb_ appears in SCOPe 2.06
  
• d2grrb_ appears in the current release, SCOPe 2.08