SCOPe 2.08: Domain d2elba2: 2elb A:274-374

Lineage for d2elba2 (2elb A:274-374)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.55: PH domain-like barrel [50728] (3 superfamilies)
   barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix

4. Superfamily b.55.1: PH domain-like [50729] (14 families)

5. Family b.55.1.1: Pleckstrin-homology domain (PH domain) [50730] (48 proteins)
   Pfam PF00169

6. Protein DCC-interacting protein 13-alpha, APPL1 [159211] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [159212] (1 PDB entry)
   Uniprot Q9UKG1 274-374

8. Domain d2elba2: 2elb A:274-374 [146896]
   Other proteins in same PDB: d2elba1

Details for d2elba2

PDB Entry: 2elb, 2.6 Å

PDB Description: Crystal Structure of the BAR-PH domain of human APPL1

PDB Compounds: (A:) Adapter protein containing PH domain, PTB domain and leucine zipper motif 1

SCOPe Domain Sequences for d2elba2:

Sequence, based on SEQRES records:

>d2elba2 b.55.1.1 (A:274-374) DCC-interacting protein 13-alpha, APPL1 {Human (Homo sapiens) [TaxId: 9606]}
nrnltrkagylnarnktglvsstwdrqfyftqggnlmsqargdvagglamdidncsvmav
dcedrrycfqitsfdgkkssilqaeskkdheewictinnis

Sequence, based on observed residues (ATOM records):

>d2elba2 b.55.1.1 (A:274-374) DCC-interacting protein 13-alpha, APPL1 {Human (Homo sapiens) [TaxId: 9606]}
nrnltrkagylnarnktgtwdrqfyftqggnlmsqargdvamdidncsvmavdcedrryc
fqitsfdgkkssilqaeskkdheewictinnis

Timeline for d2elba2:

• d2elba2 first appeared in SCOP 1.75
  
• d2elba2 appears in SCOPe 2.07