SCOP 1.75: Domain d2eg8b1: 2eg8 B:4-346

Lineage for d2eg8b1 (2eg8 B:4-346)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (18 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.4: Dihydroorotase [63917] (1 protein)

6. Protein Dihydroorotase [63918] (1 species)

7. Species Escherichia coli [TaxId:562] [63919] (5 PDB entries)

8. Domain d2eg8b1: 2eg8 B:4-346 [146831]
   automatically matched to d1xgea1
   complexed with fot, zn

Details for d2eg8b1

PDB Entry: 2eg8, 2.2 Å

PDB Description: the crystal structure of e. coli dihydroorotase complexed with 5- fluoroorotic acid

PDB Compounds: (B:) dihydroorotase

SCOP Domain Sequences for d2eg8b1:

Sequence, based on SEQRES records:

>d2eg8b1 c.1.9.4 (B:4-346) Dihydroorotase {Escherichia coli [TaxId: 562]}
sqvlkirrpddwhlhlrdgdmlktvvpytseiygraivmpnlappvttveaavayrqril
davpaghdftplmtcyltdsldpnelergfnegvftaaklypanattnsshgvtsvdaim
pvlermekigmpllvhgevthadidifdrearfiesvmeplrqrltalkvvfehittkda
adyvrdgnerlaatitpqhlmfnrnhmlvggvrphlyclpilkrnihqqalrelvasgfn
rvflgtdsapharhrkesscgcagcfnaptalgsyatvfeemnalqhfeafcsvngpqfy
glpvndtfielvreeqqvaesialtddtlvpflagetvrwsvk

Sequence, based on observed residues (ATOM records):

>d2eg8b1 c.1.9.4 (B:4-346) Dihydroorotase {Escherichia coli [TaxId: 562]}
sqvlkirrpddwhlhlrdgdmlktvvpytseiygraivmpnlappvttveaavayrqril
davpaghdftplmtcyltdsldpnelergfnegvftaaklypangvtsvdaimpvlerme
kigmpllvhgevthadidifdrearfiesvmeplrqrltalkvvfehittkdaadyvrdg
nerlaatitpqhlmfnrnhmlvggvrphlyclpilkrnihqqalrelvasgfnrvflgtd
sapharhrkesscgcagcfnaptalgsyatvfeemnalqhfeafcsvngpqfyglpvndt
fielvreeqqvaesialtddtlvpflagetvrwsvk

Timeline for d2eg8b1:

• d2eg8b1 is new in SCOP 1.75
  
• d2eg8b1 is called d2eg8b_ in SCOPe 2.01
  
• d2eg8b1 appears in the current release, SCOPe 2.08, called d2eg8b_