SCOPe 2.08: Domain d2efka1: 2efk A:10-288

Lineage for d2efka1 (2efk A:10-288)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.238: BAR/IMD domain-like [116747] (1 superfamily)
   6 helices, homodimer of 3-helical domains

4. Superfamily a.238.1: BAR/IMD domain-like [103657] (5 families)
   core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends

5. Family a.238.1.4: FCH domain [158645] (2 proteins)
   Pfam PF00611; Fes/CIP4 homology domain

6. Protein CDC42-interacting protein 4, CIP4 [158648] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [158649] (1 PDB entry)
   Uniprot Q15642 10-288

8. Domain d2efka1: 2efk A:10-288 [146815]
   Other proteins in same PDB: d2efka2

Details for d2efka1

PDB Entry: 2efk, 2.3 Å

PDB Description: Crystal structure of the EFC domain of Cdc42-interacting protein 4

PDB Compounds: (A:) Cdc42-interacting protein 4

SCOPe Domain Sequences for d2efka1:

Sequence, based on SEQRES records:

>d2efka1 a.238.1.4 (A:10-288) CDC42-interacting protein 4, CIP4 {Human (Homo sapiens) [TaxId: 9606]}
qfevlerhtqwgldlldryvkfvkerteveqayakqlrslvkkylpkrpakddpeskfsq
qqsfvqilqevndfagqrelvaenlsvrvcleltkysqemkqerkmhfqegrraqqqlen
gfkqlenskrkferdcreaekaaqtaerldqdinatkadvekakqqahlrshmaeeskne
yaaqlqrfnrdqahfyfsqmpqifdklqdmderratrlgagygllseaelevvpiiakcl
egmkvaanavdpkndshvlielhksgfarpgdvefedfs

Sequence, based on observed residues (ATOM records):

>d2efka1 a.238.1.4 (A:10-288) CDC42-interacting protein 4, CIP4 {Human (Homo sapiens) [TaxId: 9606]}
qfevlerhtqwgldlldryvkfvkerteveqayakqlrslvkkylpkeskfsqqqsfvqi
lqevndfagqrelvaenlsvrvcleltkysqemkqerkmhfqegrraqqqlengfkqlen
skrkferdcreaekaaqtaerldqdinatkadvekakqqahlrshmaeeskneyaaqlqr
fnrdqahfyfsqmpqifdklqdmderratrlgagygllseaelevvpiiakclegmkvaa
navdpkndshvlielhksgfarpgdvefedfs

Timeline for d2efka1:

• d2efka1 first appeared in SCOP 1.75
  
• d2efka1 appears in SCOPe 2.07