SCOP 1.75: Domain d2ebca2: 2ebc A:9-60,A:182-354

Lineage for d2ebca2 (2ebc A:9-60,A:182-354)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (78 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Transducin (alpha subunit) [52623] (4 species)
   common fold is interrupted with an all-alpha domain

7. Species Homo sapiens [TaxId:9606] [159560] (3 PDB entries)

8. Domain d2ebca2: 2ebc A:9-60,A:182-354 [146765]
   Other proteins in same PDB: d2ebca1
   automatically matched to d1agra2
   complexed with gdp; mutant

Details for d2ebca2

PDB Entry: 2ebc, 2.24 Å

PDB Description: Mechanism underlying the critical contribution of a switch II residue in a heterotrimeric G-protein alpha subunit during C. elegans asymmetric cell division

PDB Compounds: (A:) Guanine nucleotide-binding protein G(i), alpha-1 subunit

SCOP Domain Sequences for d2ebca2:

Sequence, based on SEQRES records:

>d2ebca2 c.37.1.8 (A:9-60,A:182-354) Transducin (alpha subunit) {Homo sapiens [TaxId: 9606]}
dkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheagXtgiveth
ftfkdlhfkmfdvdgqrserkkwihcfegvtaiifcvalsdydlvlaedeemnrmhesmk
lfdsicnnkwftdtsiilflnkkdlfeekikksplticypeyagsntyeeaaayiqcqfe
dlnkrkdtkeiythftcatdtknvqfvfdavtdviiknnlkdcglf

Sequence, based on observed residues (ATOM records):

>d2ebca2 c.37.1.8 (A:9-60,A:182-354) Transducin (alpha subunit) {Homo sapiens [TaxId: 9606]}
dkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheagXtgiveth
ftfkdlhfkmfdvdgqrseihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfds
icnnkwftdtsiilflnkkdlfeekikksplticypeyagsntyeeaaayiqcqfedlnk
rkdtkeiythftcatdtknvqfvfdavtdviiknnlkdcglf

Timeline for d2ebca2:

• d2ebca2 is new in SCOP 1.75
  
• d2ebca2 last appears in SCOPe 2.01