Lineage for d2ea4a2 (2ea4 A:110-374,A:449-478)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2214036Fold d.127: Creatinase/aminopeptidase [55919] (1 superfamily)
    duplication: composed of two very similar alpha+beta folds
  4. 2214037Superfamily d.127.1: Creatinase/aminopeptidase [55920] (2 families) (S)
  5. 2214038Family d.127.1.1: Creatinase/aminopeptidase [55921] (4 proteins)
  6. 2214087Protein Methionine aminopeptidase [55924] (6 species)
  7. 2214139Species Human (Homo sapiens) [TaxId:9606] [55927] (18 PDB entries)
    Uniprot P50579 110-478
    methionine aminopeptidase 2 contains insert domain with a circularly permuted "winged helix" fold
  8. 2214155Domain d2ea4a2: 2ea4 A:110-374,A:449-478 [146760]
    Other proteins in same PDB: d2ea4a1
    automated match to d1r58a2
    complexed with f79, mn

Details for d2ea4a2

PDB Entry: 2ea4 (more details), 2.35 Å

PDB Description: h-MetAP2 complexed with A797859
PDB Compounds: (A:) Methionine aminopeptidase 2

SCOPe Domain Sequences for d2ea4a2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2ea4a2 d.127.1.1 (A:110-374,A:449-478) Methionine aminopeptidase {Human (Homo sapiens) [TaxId: 9606]}
kvqtdppsvpicdlypngvfpkgqeceypptqdgrtaawrttseekkaldqaseeiwndf
reaaeahrqvrkyvmswikpgmtmieicekledcsrklikenglnaglafptgcslnnca
ahytpnagdttvlqyddickidfgthisgriidcaftvtfnpkydtllkavkdatntgik
cagidvrlcdvgeaiqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpiikg
geatrmeegevyaietfgstgkgvvXdikgsytaqfehtillrptckevvsrgddy

SCOPe Domain Coordinates for d2ea4a2:

Click to download the PDB-style file with coordinates for d2ea4a2.
(The format of our PDB-style files is described here.)

Timeline for d2ea4a2:

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Domains from same chain:
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d2ea4a1