SCOPe 2.08: Domain d2e64a2: 2e64 A:1-188

Lineage for d2e64a2 (2e64 A:1-188)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.104: Class II aaRS and biotin synthetases [55680] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.104.1: Class II aaRS and biotin synthetases [55681] (5 families)

5. Family d.104.1.2: Biotin holoenzyme synthetase [55707] (3 proteins)

6. Protein Biotin--[acetyl-CoA-carboxylase] ligase catalytic domain [143640] (1 species)

7. Species Pyrococcus horikoshii [TaxId:53953] [143641] (27 PDB entries)
   Uniprot O57883 1-188

8. Domain d2e64a2: 2e64 A:1-188 [146698]
   Other proteins in same PDB: d2e64a1, d2e64b1
   automated match to d2zgwa2
   mutant

Details for d2e64a2

PDB Entry: 2e64, 1.5 Å

PDB Description: crystal structure of biotin protein ligase from pyrococcus horikoshii, mutations r48a and k111a

PDB Compounds: (A:) biotin--[acetyl-CoA-carboxylase] ligase

SCOPe Domain Sequences for d2e64a2:

Sequence, based on SEQRES records:

>d2e64a2 d.104.1.2 (A:1-188) Biotin--[acetyl-CoA-carboxylase] ligase catalytic domain {Pyrococcus horikoshii [TaxId: 53953]}
mlglktsiigrrviyfqeitstnefaktsyleegtvivadkqtmghgalnrkwespeggl
wlsivlspkvpqkdlpkivflgavgvvetlkefsidgrikwpndvlvnykaiagvlvegk
gdkivlgiglnvnnkvpngatsmklelgsevpllsvfrslitnldrlylnflknpmdiln
lvrdnmil

Sequence, based on observed residues (ATOM records):

>d2e64a2 d.104.1.2 (A:1-188) Biotin--[acetyl-CoA-carboxylase] ligase catalytic domain {Pyrococcus horikoshii [TaxId: 53953]}
mlglktsiigrrviyfqeitstnefaktsyleegtvivadkqtmespegglwlsivlspk
vpqkdlpkivflgavgvvetlkefsidgrikwpndvlvnykaiagvlvegkgdkivlgig
lnvnnkvpngatsmklelgsevpllsvfrslitnldrlylnflknpmdilnlvrdnmil

Timeline for d2e64a2:

• d2e64a2 first appeared in SCOP 1.75
  
• d2e64a2 appears in SCOPe 2.07