SCOPe 2.08: Domain d2d1ia1: 2d1i A:10-373

Lineage for d2d1ia1 (2d1i A:10-373)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.22: Autophagin-like [159858] (3 proteins)
   Pfam PF03416

6. Protein Cysteine protease ATG4B [159861] (1 species)
   Autophagin-1

7. Species Human (Homo sapiens) [TaxId:9606] [159862] (2 PDB entries)
   Uniprot Q9Y4P1 10-373! Uniprot Q9Y4P1 5-354

8. Domain d2d1ia1: 2d1i A:10-373 [146447]

Details for d2d1ia1

PDB Entry: 2d1i, 2 Å

PDB Description: Structure of human Atg4b

PDB Compounds: (A:) Cysteine protease APG4B

SCOPe Domain Sequences for d2d1ia1:

Sequence, based on SEQRES records:

>d2d1ia1 d.3.1.22 (A:10-373) Cysteine protease ATG4B {Human (Homo sapiens) [TaxId: 9606]}
tlrfaefedfpetsepvwilgrkysiftekdeilsdvasrlwftyrknfpaiggtgptsd
tgwgcmlrcgqmifaqalvcrhlgrdwrwtqrkrqpdsyfsvlnafidrkdsyysihqia
qmgvgegksigqwygpntvaqvlkklavfdtwsslavhiamdntvvmeeirrlcrtsvpc
agatafpadsdrhcngfpagaevtnrpspwrplvlliplrlgltdineayvetlkhcfmm
pqslgviggkpnsahyfigyvgeeliyldphttqpaveptdgcfipdesfhcqhppcrms
iaeldpsiavgffckteddfndwcqqvkklsllggalpmfelveqqpshlacpdvlnlsl
dssd

Sequence, based on observed residues (ATOM records):

>d2d1ia1 d.3.1.22 (A:10-373) Cysteine protease ATG4B {Human (Homo sapiens) [TaxId: 9606]}
tlrfaefedfpetsepvwilgrkysiftekdeilsdvasrlwftyrknfpaiggtgptsd
tgwgcmlrcgqmifaqalvcrhlgrdwrwtqrkrqpdsyfsvlnafidrkdsyysihqia
qmgvgegksigqwygpntvaqvlkklavfdtwsslavhiamdntvvmeeirrlcrtsvpc
apspwrplvlliplrlgltdineayvetlkhcfmmpqslgviggkpnsahyfigyvgeel
iyldphttqpaveptdgcfipdesfhcqhppcrmsiaeldpsiavgffckteddfndwcq
qvkklsllggalpmfelveqqpshlacpdvlnlsldssd

Timeline for d2d1ia1:

• d2d1ia1 first appeared in SCOP 1.75
  
• d2d1ia1 appears in SCOPe 2.07