SCOPe 2.08: Domain d2cy7a_: 2cy7 A:

Lineage for d2cy7a_ (2cy7 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.22: Autophagin-like [159858] (3 proteins)
   Pfam PF03416

6. Protein automated matches [190846] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188165] (3 PDB entries)

8. Domain d2cy7a_: 2cy7 A: [146431]
   automated match to d2cy7a1

Details for d2cy7a_

PDB Entry: 2cy7, 1.9 Å

PDB Description: The crystal structure of human Atg4B

PDB Compounds: (A:) Cysteine protease APG4B

SCOPe Domain Sequences for d2cy7a_:

Sequence, based on SEQRES records:

>d2cy7a_ d.3.1.22 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tltydtlrfaefedfpetsepvwilgrkysiftekdeilsdvasrlwftyrknfpaiggt
gptsdtgwgcmlrcgqmifaqalvcrhlgrdwrwtqrkrqpdsyfsvlnafidrkdsyys
ihqiaqmgvgegksigqwygpntvaqvlkklavfdtwsslavhiamdntvvmeeirrlcr
tsvpcagatafpadsdrhcngfpagaevtnrpspwrplvlliplrlgltdineayvetlk
hcfmmpqslgviggkpnsahyfigyvgeeliyldphttqpaveptdgcfipdesfhcqhp
pcrmsiaeldpsiavgffckteddfndwcqqvkklsllggalpmfelveqqpshlacpdv
lnlsldssdverl

Sequence, based on observed residues (ATOM records):

>d2cy7a_ d.3.1.22 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tltydtlrfaefedfpetsepvwilgrkysiftekdeilsdvasrlwftyrknfpaiggt
gptsdtgwgcmlrcgqmifaqalvcrhlgrdwrwtqrkrqpdsyfsvlnafidrkdsyys
ihqiaqmgvgegksigqwygpntvaqvlkklavfdtwsslavhiamdntvvmeeirrlcr
tsvpcspwrplvlliplrlgltdineayvetlkhcfmmpqslgviggkpnsahyfigyvg
eeliyldphttqpavegcfipdesfhcqhppcrmsiaeldpsiavgffckteddfndwcq
qvkklsllpmfelveqqpdvlnlsldssdverl

Timeline for d2cy7a_:

• d2cy7a_ first appeared in SCOP 1.75, called d2cy7a1
  
• d2cy7a_ appears in SCOPe 2.07