SCOPe 2.07: Domain d2cu0a1: 2cu0 A:3-96,A:207-480

Lineage for d2cu0a1 (2cu0 A:3-96,A:207-480)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein)

6. Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (8 species)

7. Species Pyrococcus horikoshii [TaxId:53953] [159379] (1 PDB entry)
   Uniprot O58045 3-96,207-480

8. Domain d2cu0a1: 2cu0 A:3-96,A:207-480 [146425]
   disordered CBS domain is cut out
   complexed with xmp

Details for d2cu0a1

PDB Entry: 2cu0, 2.1 Å

PDB Description: Crystal structure of inosine-5'-monophosphate dehydrogenase from Pyrococcus horikoshii OT3

PDB Compounds: (A:) inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d2cu0a1:

Sequence, based on SEQRES records:

>d2cu0a1 c.1.5.1 (A:3-96,A:207-480) Inosine monophosphate dehydrogenase (IMPDH) {Pyrococcus horikoshii [TaxId: 53953]}
kfveklekaikgytfddvllipqatevepkdvdvstritpnvklnipilsaamdtvtewe
mavamaregglgvihrnmgieeqveqvkrvkraeXkyknavrdengellvaaavspfdik
raieldkagvdvivvdtahahnlkaiksmkemrqkvdadfivgnianpkavddltfadav
kvgigpgsicttrivagvgvpqitavamvadraqeyglyviadggirysgdivkaiaaga
davmlgnllagtkeapgkeviingrkykqyrgmgslgammkggaeryyqggymktrkfvp
egvegvvpyrgtvsevlyqlvgglkagmgyvgarnirelkekgefviithagikeshphd
iiitneapn

Sequence, based on observed residues (ATOM records):

>d2cu0a1 c.1.5.1 (A:3-96,A:207-480) Inosine monophosphate dehydrogenase (IMPDH) {Pyrococcus horikoshii [TaxId: 53953]}
kfveklekaikgytfddvllipqatevepkdvdvstritpnvklnipilsaamdtvtewe
mavamaregglgvihrnmgieeqveqvkrvkraeXkyknavrdengellvaaavspfdik
raieldkagvdvivvdtahahnlkaiksmkemrqkvdadfivgnianpkavddltfadav
kvgigpgsicttrivagvgvpqitavamvadraqeyglyviadggirysgdivkaiaaga
davmlgnllagtkeapgkeviingrkykqyrgmgslgammkymktrkfvpegvegvvpyr
gtvsevlyqlvgglkagmgyvgarnirelkekgefviithagikeshphdiiitneapn

Timeline for d2cu0a1:

• d2cu0a1 first appeared in SCOP 1.75
  
• d2cu0a1 appears in SCOPe 2.06
  
• d2cu0a1 appears in the current release, SCOPe 2.08