Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites |
Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families) The phosphate moiety of substrate binds in the 'common' phosphate-binding site |
Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein) |
Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (8 species) |
Species Pyrococcus horikoshii [TaxId:53953] [159379] (1 PDB entry) Uniprot O58045 3-96,207-480 |
Domain d2cu0a1: 2cu0 A:3-96,A:207-480 [146425] disordered CBS domain is cut out complexed with xmp |
PDB Entry: 2cu0 (more details), 2.1 Å
SCOPe Domain Sequences for d2cu0a1:
Sequence, based on SEQRES records: (download)
>d2cu0a1 c.1.5.1 (A:3-96,A:207-480) Inosine monophosphate dehydrogenase (IMPDH) {Pyrococcus horikoshii [TaxId: 53953]} kfveklekaikgytfddvllipqatevepkdvdvstritpnvklnipilsaamdtvtewe mavamaregglgvihrnmgieeqveqvkrvkraeXkyknavrdengellvaaavspfdik raieldkagvdvivvdtahahnlkaiksmkemrqkvdadfivgnianpkavddltfadav kvgigpgsicttrivagvgvpqitavamvadraqeyglyviadggirysgdivkaiaaga davmlgnllagtkeapgkeviingrkykqyrgmgslgammkggaeryyqggymktrkfvp egvegvvpyrgtvsevlyqlvgglkagmgyvgarnirelkekgefviithagikeshphd iiitneapn
>d2cu0a1 c.1.5.1 (A:3-96,A:207-480) Inosine monophosphate dehydrogenase (IMPDH) {Pyrococcus horikoshii [TaxId: 53953]} kfveklekaikgytfddvllipqatevepkdvdvstritpnvklnipilsaamdtvtewe mavamaregglgvihrnmgieeqveqvkrvkraeXkyknavrdengellvaaavspfdik raieldkagvdvivvdtahahnlkaiksmkemrqkvdadfivgnianpkavddltfadav kvgigpgsicttrivagvgvpqitavamvadraqeyglyviadggirysgdivkaiaaga davmlgnllagtkeapgkeviingrkykqyrgmgslgammkymktrkfvpegvegvvpyr gtvsevlyqlvgglkagmgyvgarnirelkekgefviithagikeshphdiiitneapn
Timeline for d2cu0a1: