SCOPe 2.08: Domain d2b6pa_: 2b6p A:

Lineage for d2b6pa_ (2b6p A:)

1. Root: SCOPe 2.08

2. Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)

3. Fold f.19: Aquaporin-like [81339] (1 superfamily)
   core: 8 helices, 2 short helices are surrounded by 6 long transmembrane helices

4. Superfamily f.19.1: Aquaporin-like [81338] (2 families)

5. Family f.19.1.1: Aquaporin-like [56895] (5 proteins)
   duplication: consist of two similar structural parts
   automatically mapped to Pfam PF00230

6. Protein automated matches [191175] (2 species)
   not a true protein

7. Species Cow (Bos taurus) [TaxId:9913] [225041] (2 PDB entries)

8. Domain d2b6pa_: 2b6p A: [146088]
   automated match to d1ymga1

Details for d2b6pa_

PDB Entry: 2b6p, 2.4 Å

PDB Description: X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state

PDB Compounds: (A:) lens fiber major intrinsic protein

SCOPe Domain Sequences for d2b6pa_:

Sequence, based on SEQRES records:

>d2b6pa_ f.19.1.1 (A:) automated matches {Cow (Bos taurus) [TaxId: 9913]}
welrsasfwraicaeffaslfyvffglgaslrwapgplhvlqvalafglalatlvqavgh
isgahvnpavtfaflvgsqmsllraicymvaqllgavagaavlysvtppavrgnlalntl
hpgvsvgqativeifltlqfvlcifatyderrngrlgsvalavgfsltlghlfgmyytga
gmnparsfapailtrnftnhwvywvgpvigaglgsllydfllfprlksvserlsilkgsr
psesngqpevtgepvelktqal

Sequence, based on observed residues (ATOM records):

>d2b6pa_ f.19.1.1 (A:) automated matches {Cow (Bos taurus) [TaxId: 9913]}
welrsasfwraicaeffaslfyvffglgaslrwagplhvlqvalafglalatlvqavghi
sgahvnpavtfaflvgsqmsllraicymvaqllgavagaavlysvtppavrgnlalntlh
pgvsvgqativeifltlqfvlcifatyderrngrlgsvalavgfsltlghlfgmyytgag
mnparsfapailtrnftnhwvywvgpvigaglgsllydfllfprlksvserlsilkgsrp
sesngqpevtgepvelktqal

Timeline for d2b6pa_:

• d2b6pa_ first appeared in SCOP 1.75, called d2b6pa1
  
• d2b6pa_ appears in SCOPe 2.07