SCOPe 2.08: Domain d1zu1a1: 1zu1 A:2-73

Lineage for d1zu1a1 (1zu1 A:2-73)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.37: beta-beta-alpha zinc fingers [57666] (1 superfamily)
   simple fold, consisting of the N-terminal beta-hairpin and C-terminal alpha-helical region; each part provides two zinc-coordinating residues with the observed sequences including C2H2, C2HC and CHHC

4. Superfamily g.37.1: beta-beta-alpha zinc fingers [57667] (8 families)

5. Family g.37.1.4: HkH motif-containing C2H2 finger [111436] (4 proteins)
   putative dsRNA-specific zinc finger with a helix-kink-helix (HkH) motif; the kink results from the incompatibility of the cation-coordinating H-x5-H motif with a regular alpha-helix and contributes to RNA recognition

6. Protein dsRNA-binding protein ZFa (ZNF346, JAZ) [161154] (1 species)

7. Species African clawed frog (Xenopus laevis) [TaxId:8355] [161155] (1 PDB entry)
   Uniprot Q8AVN9 2-73!Uniprot Q8AVN9 74-128

8. Domain d1zu1a1: 1zu1 A:2-73 [146026]
   complexed with zn

Details for d1zu1a1

PDB Entry: 1zu1

PDB Description: solution structure of the n-terminal zinc fingers of the xenopus laevis double stranded rna binding protein zfa

PDB Compounds: (A:) RNA binding protein ZFa

SCOPe Domain Sequences for d1zu1a1:

Sequence; same for both SEQRES and ATOM records:

>d1zu1a1 g.37.1.4 (A:2-73) dsRNA-binding protein ZFa (ZNF346, JAZ) {African clawed frog (Xenopus laevis) [TaxId: 8355]}
adefgngdaldlpvgkdavnslirenshifsdtqckvcsavlisesqklahyqsrkhank
vrrymainqged

Timeline for d1zu1a1:

• d1zu1a1 first appeared in SCOP 1.75
  
• d1zu1a1 appears in SCOPe 2.07