SCOPe 2.08: Domain d1vrda1: 1vrd A:1-85,A:213-457

Lineage for d1vrda1 (1vrd A:1-85,A:213-457)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein)

6. Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (8 species)

7. Species Thermotoga maritima [TaxId:2336] [159378] (1 PDB entry)
   Uniprot Q9X168 1-85,213-457

8. Domain d1vrda1: 1vrd A:1-85,A:213-457 [145788]
   disordered CBS domain is cut out

Details for d1vrda1

PDB Entry: 1vrd, 2.18 Å

PDB Description: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347) from thermotoga maritima at 2.18 a resolution

PDB Compounds: (A:) inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d1vrda1:

Sequence, based on SEQRES records:

>d1vrda1 c.1.5.1 (A:1-85,A:213-457) Inosine monophosphate dehydrogenase (IMPDH) {Thermotoga maritima [TaxId: 2336]}
mkealtfddvllvpqysevlpkdvkidtrltrqiriniplvsaamdtvteaalakalare
ggigiihknltpdeqarqvsivkktXrllvgaavgtspetmerveklvkagvdvividta
hghsrrvietlemikadypdlpvvagnvatpegtealikagadavkvgvgpgsicttrvv
agvgvpqltavmecsevarkydvpiiadggirysgdivkalaagaesvmvgsifagteea
pgetilyqgrkykayrgmgslgamrsgsadrygqegenkfvpegiegmvpykgtvkdvvh
qlvgglrsgmgyigartikelqekavfvkit

Sequence, based on observed residues (ATOM records):

>d1vrda1 c.1.5.1 (A:1-85,A:213-457) Inosine monophosphate dehydrogenase (IMPDH) {Thermotoga maritima [TaxId: 2336]}
mkealtfddvllvpqysevlpkdvkidtrltrqiriniplvsaamdtvteaalakalare
ggigiihknltpdeqarqvsivkktXrllvgaavgtspetmerveklvkagvdvividta
hghsrrvietlemikadypdlpvvagnvatpegtealikagadavkvgvgpgsicttrvv
agvgvpqltavmecsevarkydvpiiadggirysgdivkalaagaesvmvgsifagteea
pgetilyqgrkykayrgmgiegmvpykgtvkdvvhqlvgglrsgmgyigartikelqeka
vfvkit

Timeline for d1vrda1:

• d1vrda1 first appeared in SCOP 1.75
  
• d1vrda1 appears in SCOPe 2.07