SCOPe 2.07: Domain d2z0da1: 2z0d A:5-354

Lineage for d2z0da1 (2z0d A:5-354)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.22: Autophagin-like [159858] (3 proteins)
   Pfam PF03416

6. Protein Cysteine protease ATG4B [159861] (1 species)
   Autophagin-1

7. Species Human (Homo sapiens) [TaxId:9606] [159862] (2 PDB entries)
   Uniprot Q9Y4P1 10-373! Uniprot Q9Y4P1 5-354

8. Domain d2z0da1: 2z0d A:5-354 [145769]
   Other proteins in same PDB: d2z0db_

Details for d2z0da1

PDB Entry: 2z0d, 1.9 Å

PDB Description: the crystal structure of human atg4b- lc3(1-120) complex

PDB Compounds: (A:) Cysteine protease ATG4B

SCOPe Domain Sequences for d2z0da1:

Sequence, based on SEQRES records:

>d2z0da1 d.3.1.22 (A:5-354) Cysteine protease ATG4B {Human (Homo sapiens) [TaxId: 9606]}
tltydtlrfaefedfpetsepvwilgrkysiftekdeilsdvasrlwftyrknfpaiggt
gptsdtgwgcmlrcgqmifaqalvcrhlgrdwrwtqrkrqpdsyfsvlnafidrkdsyys
ihqiaqmgvgegksigqwygpntvaqvlkklavfdtwsslavhiamdntvvmeeirrlcr
tsvpcagatafpadsdrhcngfpagaevtnrpspwrplvlliplrlgltdineayvetlk
hcfmmpqslgviggkpnsahyfigyvgeeliyldpattqpaveptdgcfipdesfhcqhp
pcrmsiaeldpsiavgffckteddfndwcqqvkklsllggalpmfelveq

Sequence, based on observed residues (ATOM records):

>d2z0da1 d.3.1.22 (A:5-354) Cysteine protease ATG4B {Human (Homo sapiens) [TaxId: 9606]}
tltydtlrfaefedfpetsepvwilgrkysiftekdeilsdvasrlwftyrknfpaiggt
gptsdtgwgcmlrcgqmifaqalvcrhlgrdwrwtqrkrqpdsyfsvlnafidrkdsyys
ihqiaqmgvgegksigqwygpntvaqvlkklavfdtwsslavhiamdntvvmeeirrlcr
tspwrplvlliplrlgltdineayvetlkhcfmmpqslgviggkpnsahyfigyvgeeli
yldpattqpavepipdesfhcqhppcrmsiaeldpsiavgffckteddfndwcqqvkkla
lpmfelveq

Timeline for d2z0da1:

• d2z0da1 first appeared in SCOP 1.75
  
• d2z0da1 appears in SCOPe 2.06
  
• d2z0da1 appears in the current release, SCOPe 2.08