SCOPe 2.08: Domain d2ozbe_: 2ozb E:

Lineage for d2ozbe_ (2ozb E:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.183: Nop domain [89123] (1 superfamily)
   multihelical; array of longer and shorter helices; contains an alpha-hairpin dimerisation subdomain

4. Superfamily a.183.1: Nop domain [89124] (2 families)

5. Family a.183.1.1: Nop domain [89125] (2 proteins)
   putative snoRNA binding domain

6. Protein U4/U6 small nuclear ribonucleoprotein Prp31 [158762] (2 species)
   contains insertion of a small 4-helical bundle at the tip of a long alpha-hairpin arm; this insertion approximately corresponds to the NOSIC (NUC001) domain; Pfam PF08060

7. Species Human (Homo sapiens) [TaxId:9606] [158763] (2 PDB entries)
   Uniprot Q8WWY3 85-333

8. Domain d2ozbe_: 2ozb E: [145743]
   Other proteins in same PDB: d2ozba1, d2ozbd1
   automated match to d2ozbb1
   protein/RNA complex; complexed with ca
   has additional subdomain(s) that are not in the common domain

Details for d2ozbe_

PDB Entry: 2ozb, 2.6 Å

PDB Description: structure of a human prp31-15.5k-u4 snrna complex

PDB Compounds: (E:) U4/U6 small nuclear ribonucleoprotein Prp31

SCOPe Domain Sequences for d2ozbe_:

Sequence, based on SEQRES records:

>d2ozbe_ a.183.1.1 (E:) U4/U6 small nuclear ribonucleoprotein Prp31 {Human (Homo sapiens) [TaxId: 9606]}
eaapeyrvivdannltveienelniihkfirdkyskrfpeleslvpnaldyirtvkelgn
sldkcknnenlqqiltnatimvvsvtasttqgqqlseeelerleeacdmalelnaskhri
yeyvesrmsfiapnlsiiigastaakimgvaggltnlskmpacnimllgaqrktlsgfss
tsvlphtgyiyhsdivqslppdlrrkaarlvaakctlaarvdsfhestegkvgyelkdei
erkfdkwqe

Sequence, based on observed residues (ATOM records):

>d2ozbe_ a.183.1.1 (E:) U4/U6 small nuclear ribonucleoprotein Prp31 {Human (Homo sapiens) [TaxId: 9606]}
eaapeyrvivdannltveienelniihkfirdkyskrfpeleslvpnaldyirtvkelgn
sldkcknnenlqqiltnatimvvsvtasttqgqqlseeelerleeacdmalelnaskhri
yeyvesrmsfiapnlsiiigastaakimgvaggltnlskmpacnimllgaqrsvlphtgy
iyhsdivqslppdlrrkaarlvaakctlaarvdsfhestegkvgyelkdeierkfdkwqe

Timeline for d2ozbe_:

• d2ozbe_ first appeared in SCOP 1.75, called d2ozbe1
  
• d2ozbe_ appears in SCOPe 2.07