SCOPe 2.06: Domain d2ovrb1: 2ovr B:2263-2364

Lineage for d2ovrb1 (2ovr B:2263-2364)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.158: F-box domain [81385] (1 superfamily)
   multihelical; interlocked heterodimer with the Skp1 dimerisation domain

4. Superfamily a.158.1: F-box domain [81383] (1 family)

5. Family a.158.1.1: F-box domain [81381] (4 proteins)

6. Protein F-box/WD repeat-containing protein 7, FBXW7 [158808] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [158809] (3 PDB entries)
   Uniprot Q969H0 263-364

8. Domain d2ovrb1: 2ovr B:2263-2364 [145735]
   Other proteins in same PDB: d2ovra1, d2ovra2, d2ovrb2
   automatically matched to 2OVP B:2263-2364
   complexed with so4

Details for d2ovrb1

PDB Entry: 2ovr, 2.5 Å

PDB Description: Structure of the Skp1-Fbw7-CyclinEdegN complex

PDB Compounds: (B:) F-box/WD repeat protein 7

SCOPe Domain Sequences for d2ovrb1:

Sequence, based on SEQRES records:

>d2ovrb1 a.158.1.1 (B:2263-2364) F-box/WD repeat-containing protein 7, FBXW7 {Human (Homo sapiens) [TaxId: 9606]}
tqvkhmmqviepqfqrdfisllpkelalyvlsflepkdllqaaqtcrywrilaednllwr
ekckeegideplhikrrkvikpgfihspwksayirqhridtn

Sequence, based on observed residues (ATOM records):

>d2ovrb1 a.158.1.1 (B:2263-2364) F-box/WD repeat-containing protein 7, FBXW7 {Human (Homo sapiens) [TaxId: 9606]}
tqvkhmmqviepqfqrdfisllpkelalyvlsflepkdllqaaqtcrywrilaednllwr
ekckeegideplhikrvikpgfihspwksayirqhridtn

Timeline for d2ovrb1:

• d2ovrb1 first appeared in SCOP 1.75
  
• d2ovrb1 appears in SCOPe 2.05
  
• d2ovrb1 appears in SCOPe 2.07
  
• d2ovrb1 appears in the current release, SCOPe 2.08