Lineage for d2iw8c_ (2iw8 C:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673984Protein automated matches [190091] (13 species)
    not a true protein
  7. 1674055Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)
  8. 1674378Domain d2iw8c_: 2iw8 C: [145545]
    Other proteins in same PDB: d2iw8a1, d2iw8b1, d2iw8b2, d2iw8d1, d2iw8d2
    automated match to d1ogua_
    complexed with 4sp, sgm; mutant

Details for d2iw8c_

PDB Entry: 2iw8 (more details), 2.3 Å

PDB Description: structure of human thr160-phospho cdk2-cyclin a f82h-l83v-h84d mutant with an o6-cyclohexylmethylguanine inhibitor
PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d2iw8c_:

Sequence, based on SEQRES records: (download)

>d2iw8c_ d.144.1.7 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfehvdqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Sequence, based on observed residues (ATOM records): (download)

>d2iw8c_ d.144.1.7 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfehvdqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgvppldedgrsllsqmlhyd
pnkrisakaalahpffqdvtkpvphl

SCOPe Domain Coordinates for d2iw8c_:

Click to download the PDB-style file with coordinates for d2iw8c_.
(The format of our PDB-style files is described here.)

Timeline for d2iw8c_: