Lineage for d2gjxh2 (2gjx H:23-166)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. Superfamily d.92.2: beta-N-acetylhexosaminidase-like domain [55545] (4 families) (S)
    contains similar fold but lacks its catalytic centre
  5. Family d.92.2.1: beta-N-acetylhexosaminidase domain [55546] (4 proteins)
    family GH20
  6. Protein beta-hexosaminidase A [160560] (1 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [160561] (2 PDB entries)
    Uniprot P06865 23-166
  8. Domain d2gjxh2: 2gjx H:23-166 [145209]
    Other proteins in same PDB: d2gjxa1, d2gjxb1, d2gjxb2, d2gjxc1, d2gjxc2, d2gjxd1, d2gjxe1, d2gjxf1, d2gjxf2, d2gjxg1, d2gjxg2, d2gjxh1
    automated match to d2gjxa2
    complexed with nag, so4

Details for d2gjxh2

PDB Entry: 2gjx (more details), 2.8 Å

PDB Description: crystallographic structure of human beta-hexosaminidase a
PDB Compounds: (H:) Beta-hexosaminidase alpha chain

SCOPe Domain Sequences for d2gjxh2:

Sequence, based on SEQRES records: (download)

>d2gjxh2 d.92.2.1 (H:23-166) beta-hexosaminidase A {Human (Homo sapiens) [TaxId: 9606]}
lwpwpqnfqtsdqryvlypnnfqfqydvssaaqpgcsvldeafqryrdllfgsgswprpy
ltgkrhtleknvlvvsvvtpgcnqlptlesvenytltinddqclllsetvwgalrgletf
sqlvwksaegtffinkteiedfpr

Sequence, based on observed residues (ATOM records): (download)

>d2gjxh2 d.92.2.1 (H:23-166) beta-hexosaminidase A {Human (Homo sapiens) [TaxId: 9606]}
lwpwpqnfqtsdqryvlypnnfqfqydvssaaqpgcsvldeafqryrdllfgtleknvlv
vsvvtpgcnqlptlesvenytltinddqclllsetvwgalrgletfsqlvwksaegtffi
nkteiedfpr

SCOPe Domain Coordinates for d2gjxh2 are not available.

Timeline for d2gjxh2:

Domains from same chain:
(mouse over for more information)
d2gjxh1
Domains from other chains:
(mouse over for more information)
d2gjxa1, d2gjxa2, d2gjxb1, d2gjxb2, d2gjxc1, d2gjxc2, d2gjxd1, d2gjxd2, d2gjxe1, d2gjxe2, d2gjxf1, d2gjxf2, d2gjxg1, d2gjxg2