SCOPe 2.08: Domain d2fjub2: 2fju B:678-799

Lineage for d2fjub2 (2fju B:678-799)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.7: C2 domain-like [49561] (5 superfamilies)
   sandwich; 8 strands in 2 sheets; greek-key

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (4 families)
   two constituent families are related by circular permutation

5. Family b.7.1.1: PLC-like (P variant) [49563] (12 proteins)

6. Protein Phospholipase C-beta-2 [158944] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [158945] (2 PDB entries)
   Uniprot Q00722 678-799

8. Domain d2fjub2: 2fju B:678-799 [145171]
   Other proteins in same PDB: d2fjua_, d2fjub1, d2fjub3, d2fjub4
   complexed with ca, gsp, mg

Details for d2fjub2

PDB Entry: 2fju, 2.2 Å

PDB Description: Activated Rac1 bound to its effector phospholipase C beta 2

PDB Compounds: (B:) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2

SCOPe Domain Sequences for d2fjub2:

Sequence; same for both SEQRES and ATOM records:

>d2fjub2 b.7.1.1 (B:678-799) Phospholipase C-beta-2 {Human (Homo sapiens) [TaxId: 9606]}
ttlsitvisgqflsersvrtyvevelfglpgdpkrryrtklspstnsinpvwkeepfvfe
kilmpelaslrvavmeegnkflghriipinalnsgyhhlclhsesnmpltmpalfiflem
kd

Timeline for d2fjub2:

• d2fjub2 first appeared in SCOP 1.75
  
• d2fjub2 appears in SCOPe 2.07