Lineage for d2fd6u3 (2fd6 U:92-188)

  1. Root: SCOP 1.75
  2. 888632Class g: Small proteins [56992] (90 folds)
  3. 890226Fold g.7: Snake toxin-like [57301] (1 superfamily)
    disulfide-rich fold: nearly all-beta
  4. 890227Superfamily g.7.1: Snake toxin-like [57302] (3 families) (S)
  5. 890414Family g.7.1.3: Extracellular domain of cell surface receptors [57354] (6 proteins)
  6. 890476Protein Urokinase plasminogen activator surface receptor, UPAR [161130] (1 species)
    duplication; comprises three domains of this fold
  7. 890477Species Human (Homo sapiens) [TaxId:9606] [161131] (4 PDB entries)
    Uniprot Q03405 111-210! Uniprot Q03405 114-210! Uniprot Q03405 211-297! Uniprot Q03405 211-301! Uniprot Q03405 23-102! Uniprot Q03405 23-104
  8. 890480Domain d2fd6u3: 2fd6 U:92-188 [145161]
    Other proteins in same PDB: d2fd6a1, d2fd6a2, d2fd6h1, d2fd6h2, d2fd6l1, d2fd6l2
    complexed with edo, etx, fuc, nag, pg4, pge, so4

Details for d2fd6u3

PDB Entry: 2fd6 (more details), 1.9 Å

PDB Description: Structure of Human Urokinase Plasminogen Activator in Complex with Urokinase Receptor and an anti-upar antibody at 1.9 A
PDB Compounds: (U:) Urokinase plasminogen activator surface receptor

SCOP Domain Sequences for d2fd6u3:

Sequence, based on SEQRES records: (download)

>d2fd6u3 g.7.1.3 (U:92-188) Urokinase plasminogen activator surface receptor, UPAR {Human (Homo sapiens) [TaxId: 9606]}
yleciscgssdmscergrhqslqcrspeeqcldvvthwiqegeegrpkddrhlrgcgylp
gcpgsngfhnndtfhflkccnttkcnegpilelenlp

Sequence, based on observed residues (ATOM records): (download)

>d2fd6u3 g.7.1.3 (U:92-188) Urokinase plasminogen activator surface receptor, UPAR {Human (Homo sapiens) [TaxId: 9606]}
yleciscgssdmscergrhqslqcrspeeqcldvvthwddrhlrgcgylpgcpgsngfhn
ndtfhflkccnttkcnegpilelenlp

SCOP Domain Coordinates for d2fd6u3:

Click to download the PDB-style file with coordinates for d2fd6u3.
(The format of our PDB-style files is described here.)

Timeline for d2fd6u3: