SCOPe 2.08: Domain d2f3ci1: 2f3c I:5-50

Lineage for d2f3ci1 (2f3c I:5-50)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.68: Kazal-type serine protease inhibitors [100894] (1 superfamily)

4. Superfamily g.68.1: Kazal-type serine protease inhibitors [100895] (3 families)
   conserved core consists of a helix and a loop crosslinked with two disulfides

5. Family g.68.1.1: Ovomucoid domain III-like [57468] (11 proteins)

6. Protein Blood-sucking insect-derived tryptase inhibitor [57476] (2 species)
   duplication: contains two domains of this fold

7. Species Triatoma infestans [TaxId:30076] [161138] (2 PDB entries)
   Uniprot Q95P16 170-222! Uniprot Q95P16 5-50
   infestin

8. Domain d2f3ci1: 2f3c I:5-50 [145130]
   Other proteins in same PDB: d2f3ce_
   infestin 1
   complexed with ca, so4

Details for d2f3ci1

PDB Entry: 2f3c, 2.5 Å

PDB Description: crystal structure of infestin 1, a kazal-type serineprotease inhibitor, in complex with trypsin

PDB Compounds: (I:) thrombin inhibitor infestin

SCOPe Domain Sequences for d2f3ci1:

Sequence; same for both SEQRES and ATOM records:

>d2f3ci1 g.68.1.1 (I:5-50) Blood-sucking insect-derived tryptase inhibitor {Triatoma infestans [TaxId: 30076]}
dcacprvlhrvcgsdgntysnpctldcakhegkpdlvqvhegpcdp

Timeline for d2f3ci1:

• d2f3ci1 first appeared in SCOP 1.75
  
• d2f3ci1 appears in SCOPe 2.07