SCOPe 2.08: Domain d2dsrb_: 2dsr B:

Lineage for d2dsrb_ (2dsr B:)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.9: Growth factor receptor domain [57184] (2 families)

5. Family g.3.9.1: Growth factor receptor domain [57185] (11 proteins)
   Pfam PF00757; Pfam PF14843; Pfam PF15913
   heterogeneous fold; applies to domains that adopt a different fold than the exemplar domain but has similar sequence and number of secondary structures
   

6. Protein automated matches [190609] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187631] (7 PDB entries)

8. Domain d2dsrb_: 2dsr B: [145093]
   Other proteins in same PDB: d2dsrg1, d2dsri_
   automated match to d2dspb1

Details for d2dsrb_

PDB Entry: 2dsr, 2.1 Å

PDB Description: Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins

PDB Compounds: (B:) Insulin-like growth factor-binding protein 4

SCOPe Domain Sequences for d2dsrb_:

Sequence; same for both SEQRES and ATOM records:

>d2dsrb_ g.3.9.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aihcppcseeklarcrppvgceelvrepgcgccatcalglgmpcgvytprcgsglrcypp
rgvekplhtlmhgqgvcmel

Timeline for d2dsrb_:

• d2dsrb_ first appeared in SCOP 1.75, called d2dsrb1
  
• d2dsrb_ appears in SCOPe 2.07