Lineage for d2dd8l1 (2dd8 L:3-108)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2019185Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 2019263Species Human (Homo sapiens), cluster 5 [TaxId:9606] [88540] (7 PDB entries)
    Uniprot Q8N355 20-230 # 94% sequence identity; natural chimera: antibody light chain (Fab HYB3)
  8. 2019268Domain d2dd8l1: 2dd8 L:3-108 [145075]
    Other proteins in same PDB: d2dd8h1, d2dd8h2, d2dd8l2, d2dd8s1
    complexed with nag, po4

Details for d2dd8l1

PDB Entry: 2dd8 (more details), 2.3 Å

PDB Description: Crystal Structure of SARS-CoV Spike Receptor-Binding Domain Complexed with Neutralizing Antibody
PDB Compounds: (L:) IGG Light chain

SCOPe Domain Sequences for d2dd8l1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2dd8l1 b.1.1.1 (L:3-108) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 5 [TaxId: 9606]}

SCOPe Domain Coordinates for d2dd8l1:

Click to download the PDB-style file with coordinates for d2dd8l1.
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Timeline for d2dd8l1: