Lineage for d2agjh1 (2agj H:1-120)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2017323Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2017327Species Engineered (including hybrid species) [88562] (68 PDB entries)
    SQ NA # humanized antidoby; bactericidal Fab-h6831 ! SQ NA # humanized antibody ! SQ NA # Humanized antibody ! SQ NA # engineered antibody
  8. 2017394Domain d2agjh1: 2agj H:1-120 [144806]
    Other proteins in same PDB: d2agjh2, d2agjl1, d2agjl2
    annotated as human, this domain has greater sequence similarity to mouse VH domains

Details for d2agjh1

PDB Entry: 2agj (more details), 2.6 Å

PDB Description: Crystal Structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody
PDB Compounds: (H:) Yvo Fab, Heavy Chain

SCOPe Domain Sequences for d2agjh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2agjh1 b.1.1.1 (H:1-120) Immunoglobulin heavy chain variable domain, VH {Engineered (including hybrid species)}

SCOPe Domain Coordinates for d2agjh1:

Click to download the PDB-style file with coordinates for d2agjh1.
(The format of our PDB-style files is described here.)

Timeline for d2agjh1:

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