SCOP 1.75: Domain d1y8na2: 1y8n A:177-301

Lineage for d1y8na2 (1y8n A:177-301)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (4 families)

5. Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain [69804] (2 proteins)

6. Protein Pyruvate dehydrogenase kinase [69807] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [160702] (5 PDB entries)
   Uniprot Q15120 177-301

8. Domain d1y8na2: 1y8n A:177-301 [144602]
   Other proteins in same PDB: d1y8na1, d1y8nb1
   complexed with k, lpa

Details for d1y8na2

PDB Entry: 1y8n, 2.6 Å

PDB Description: Crystal structure of the PDK3-L2 complex

PDB Compounds: (A:) [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3

SCOP Domain Sequences for d1y8na2:

Sequence; same for both SEQRES and ATOM records:

>d1y8na2 d.122.1.4 (A:177-301) Pyruvate dehydrogenase kinase {Human (Homo sapiens) [TaxId: 9606]}
npvhpkhigsidptcnvadvvkdayetakmlceqyylvapeleveefnakapdkpiqvvy
vpshlfhmlfelfknsmratvelyedrkegypavktlvtlgkedlsikisdlgggvplrk
idrlf

Timeline for d1y8na2:

• d1y8na2 is new in SCOP 1.75
  
• d1y8na2 appears in SCOPe 2.01
  
• d1y8na2 appears in the current release, SCOPe 2.08