Lineage for d1y6nl1 (1y6n L:12-157)

  1. Root: SCOP 1.75
  2. 758332Class a: All alpha proteins [46456] (284 folds)
  3. 767022Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 767023Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 767210Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (8 proteins)
    contains an additional helix in one of the crossover connections
  6. 767259Protein Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) [47306] (3 species)
    intertwined dimer, similar to interferon-gamma
  7. 767260Species Epstein-Barr virus [TaxId:10376] [47308] (3 PDB entries)
  8. 767262Domain d1y6nl1: 1y6n L:12-157 [144600]
    Other proteins in same PDB: d1y6nr1, d1y6nr2

Details for d1y6nl1

PDB Entry: 1y6n (more details), 2.7 Å

PDB Description: crystal structure of epstein-barr virus il-10 mutant (a87i) complexed with the soluble il-10r1 chain
PDB Compounds: (L:) Viral interleukin-10 homolog

SCOP Domain Sequences for d1y6nl1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1y6nl1 a.26.1.3 (L:12-157) Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) {Epstein-Barr virus [TaxId: 10376]}

SCOP Domain Coordinates for d1y6nl1:

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Timeline for d1y6nl1: