Lineage for d1y6nl1 (1y6n L:12-157)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2315782Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 2315783Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 2316095Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 proteins)
    contains an additional helix in one of the crossover connections
  6. 2316162Protein Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) [47306] (3 species)
    intertwined dimer, similar to interferon-gamma
  7. 2316163Species Epstein-Barr virus [TaxId:10376] [47308] (3 PDB entries)
  8. 2316165Domain d1y6nl1: 1y6n L:12-157 [144600]
    Other proteins in same PDB: d1y6nr1, d1y6nr2

Details for d1y6nl1

PDB Entry: 1y6n (more details), 2.7 Å

PDB Description: Crystal structure of Epstein-Barr virus IL-10 mutant (A87I) complexed with the soluble IL-10R1 chain
PDB Compounds: (L:) Viral interleukin-10 homolog

SCOPe Domain Sequences for d1y6nl1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1y6nl1 a.26.1.3 (L:12-157) Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) {Epstein-Barr virus [TaxId: 10376]}

SCOPe Domain Coordinates for d1y6nl1:

Click to download the PDB-style file with coordinates for d1y6nl1.
(The format of our PDB-style files is described here.)

Timeline for d1y6nl1: