SCOPe 2.08: Domain d1x75a1: 1x75 A:363-494

Lineage for d1x75a1 (1x75 A:363-494)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.11: Type II DNA topoisomerase C-terminal domain-like [56718] (1 superfamily)
   4 domains: (1) toprim alpha/beta; (2) "winged helix"-like; (3) alpha+beta; (4) all-alpha

4. Superfamily e.11.1: Type II DNA topoisomerase C-terminal domain-like [56719] (2 families)

5. Family e.11.1.1: Type II DNA topoisomerase C-terminal domain-like [56720] (3 proteins)
   domain 2 contains the catalytic tyrosine residue

6. Protein DNA Gyrase A [56723] (2 species)

7. Species Escherichia coli [TaxId:562] [56724] (5 PDB entries)

8. Domain d1x75a1: 1x75 A:363-494 [144576]
   Other proteins in same PDB: d1x75c_, d1x75d_
   CcdB-interacting subdomain only
   fragment; missing more than one-third of the common structure and/or sequence

Details for d1x75a1

PDB Entry: 1x75, 2.8 Å

PDB Description: CcdB:GyrA14 complex

PDB Compounds: (A:) DNA gyrase subunit A

SCOPe Domain Sequences for d1x75a1:

Sequence, based on SEQRES records:

>d1x75a1 e.11.1.1 (A:363-494) DNA Gyrase A {Escherichia coli [TaxId: 562]}
trrtifelrkardrahilealavalanidpiielirhaptpaeaktalvanpwqlgnvaa
mleragddaarpewlepefgvrdglyylteqqaqaildlrlqkltgleheklldeykell
dqiaellrilgs

Sequence, based on observed residues (ATOM records):

>d1x75a1 e.11.1.1 (A:363-494) DNA Gyrase A {Escherichia coli [TaxId: 562]}
trrtifelrkardrahilealavalanidpiielirhaptpaeaktalvanpwqlnvaam
leddaarpewlepefgvrdglyylteqqaqaildlrlqkltgleheklldeykelldqia
ellrilgs

Timeline for d1x75a1:

• d1x75a1 first appeared in SCOP 1.75
  
• d1x75a1 appears in SCOPe 2.07