Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.37: beta-beta-alpha zinc fingers [57666] (1 superfamily) simple fold, consisting of the N-terminal beta-hairpin and C-terminal alpha-helical region; each part provides two zinc-coordinating residues with the observed sequences including C2H2, C2HC and CHHC

4. Superfamily g.37.1: beta-beta-alpha zinc fingers [57667] (8 families)

5. Family g.37.1.4: HkH motif-containing C2H2 finger [111436] (4 proteins) putative dsRNA-specific zinc finger with a helix-kink-helix (HkH) motif; the kink results from the incompatibility of the cation-coordinating H-x5-H motif with a regular alpha-helix and contributes to RNA recognition

6. Protein Zinc finger protein 593, ZNF593 [144151] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [144152] (1 PDB entry) Uniprot O00488 28-94