SCOPe 2.06: Family d.157.1.10: beta-CASP RNA-metabolising hydrolases

Lineage for Family d.157.1.10: beta-CASP RNA-metabolising hydrolases

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.157: Metallo-hydrolase/oxidoreductase [56280] (1 superfamily)
   duplication of beta(4)-alpha-beta-alpha motif; 4 layers a/b/b/a; mixed beta-sheets

4. Superfamily d.157.1: Metallo-hydrolase/oxidoreductase [56281] (15 families)

5. Family d.157.1.10: beta-CASP RNA-metabolising hydrolases [143927] (4 proteins)
   contains insertion of a single helicase-like alpha/beta domain (from (52540)) but without the P-loop motif

Proteins:

1. Cleavage and polyadenylation specificity factor subunit 3 [160856] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [160857] (2 PDB entries)
     Uniprot Q9UKF6 9-459

2. Cleavage factor two protein 2, CFT2 [160852] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [160853] (1 PDB entry)
     Uniprot Q12102 1-422,627-717

3. Hypothetical protein EF2904 [143928] (1 species)

   • Species Enterococcus faecalis [TaxId:1351] [143929] (1 PDB entry)
     Uniprot Q82ZZ3 5-429

4. Putative RNA-degradation protein TTHA0252 [160854] (1 species)

   • Species Thermus thermophilus [TaxId:274] [160855] (14 PDB entries)
     Uniprot Q5SLP1 1-431

More info for Family d.157.1.10: beta-CASP RNA-metabolising hydrolases

Timeline for Family d.157.1.10: beta-CASP RNA-metabolising hydrolases:

• Family d.157.1.10: beta-CASP RNA-metabolising hydrolases first appeared in SCOP 1.73, called Family d.157.1.10: EF2904-like
  
• Family d.157.1.10: beta-CASP RNA-metabolising hydrolases appears in SCOPe 2.05
  
• Family d.157.1.10: beta-CASP RNA-metabolising hydrolases appears in SCOPe 2.07
  
• Family d.157.1.10: beta-CASP RNA-metabolising hydrolases appears in the current release, SCOPe 2.08