Lineage for Species: Plasmodium vivax [TaxId: 5855]

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.96: T-fold [55619] (2 superfamilies) beta(2)-alpha(2)-beta(2); 2 layers: alpha/beta; antiparallel sheet 1234 tunnel-shaped: its known members form wide oligomeric barrels different sizes

4. Superfamily d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like [55620] (5 families) bind purine or pterin in topologically similar sites between subunits

5. Family d.96.1.2: 6-pyruvoyl tetrahydropterin synthase [55625] (2 proteins)

6. Protein 6-pyruvoyl tetrahydropterin synthase [55626] (4 species) beta-sheets of three subunits form a barrel, closed: n=12, S=12

7. Species Plasmodium vivax [TaxId:5855] [143629] (1 PDB entry) 73% similarity to the Plasmodium falciparum enzyme