Lineage for Protein: Presequence protease 1, PREP1

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1943314Fold d.185: LuxS/MPP-like metallohydrolase [63410] (1 superfamily)
    core: beta-alpha-beta(2)-alpha(2); 2 layers: alpha/beta
  4. 1943315Superfamily d.185.1: LuxS/MPP-like metallohydrolase [63411] (3 families) (S)
    Share the same "active site motif" HxxEH located in the first core helix, but differ in one of the zinc-binding residues
  5. 1943316Family d.185.1.1: MPP-like [63412] (7 proteins)
    Common fold elaborated with many additional structures; duplication: each family member consists of two similar domains of beta(2)-alpha(2)-beta(2)-alpha(5)-beta structure, but only the N-terminal domain of MPP beta chain binds the catalytic metal
  6. 1943529Protein Presequence protease 1, PREP1 [143498] (1 species)
    duplication: comprises four domains of this fold; similar to the MPP alpha-beta heterodimer

Species:

More info for Protein Presequence protease 1, PREP1 from d.185.1.1: MPP-like

Timeline for Protein Presequence protease 1, PREP1 from d.185.1.1: MPP-like: