SCOPe 2.08: Family d.294.1.1: Eukaryotic EndoU ribonuclease

Lineage for Family d.294.1.1: Eukaryotic EndoU ribonuclease

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.294: EndoU-like [142876] (1 superfamily)
   comprises several helices and two three-stranded antiparallel beta-sheets; similar architecture to the RNase A-like fold (54075)

4. Superfamily d.294.1: EndoU-like [142877] (3 families)
   similarity to the RNase A-like superfamily (54076) extends to the active site location and architecture; the two structural cores of the RNase A and EndoU superfamilies are interrelated by a topological permutation - transposition of two pereferial beta-strands, suggesting possible distant homology of the two superfamilies (and their unification in a hyperfamily)

5. Family d.294.1.1: Eukaryotic EndoU ribonuclease [142878] (2 proteins)
   PfamB PB010233; common fold decorated with additional structures
   automatically mapped to Pfam PF09412

Proteins:

1. EndoU [142879] (1 species)

   • Species African clawed frog (Xenopus laevis) [TaxId:8355] [142880] (1 PDB entry)
     Uniprot Q8JFY9 6-289

2. automated matches [190536] (1 species)
   not a true protein

   • Species African clawed frog (Xenopus laevis) [TaxId:8355] [187504] (1 PDB entry)

More info for Family d.294.1.1: Eukaryotic EndoU ribonuclease

Timeline for Family d.294.1.1: Eukaryotic EndoU ribonuclease:

• Family d.294.1.1: Eukaryotic EndoU ribonuclease first appeared in SCOP 1.73
  
• Family d.294.1.1: Eukaryotic EndoU ribonuclease appears in SCOPe 2.07