Lineage for Superfamily d.294.1: EndoU-like

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 741509Fold d.294: EndoU-like [142876] (1 superfamily)
    comprises several helices and two three-stranded antiparallel beta-sheets; similar architecture to the RNase A-like fold (scop_cf 54075)
  4. 741510Superfamily d.294.1: EndoU-like [142877] (2 families) (S)
    similarity to the RNase A-like superfamily (scop_sf 54076) extends to the active site location and architecture; the two structural cores of the RNase A and EndoU superfamilies are interrelated by a topological permutation - transposition of two pereferial beta-strands, suggesting possible distant homology of the two superfamilies (and their unification in a hyperfamily)


  1. 741511d.294.1.1: Eukaryotic EndoU ribonuclease [142878] (1 protein)
    PfamB 010233; common fold decorated with additional structures
  2. 741517d.294.1.2: Nsp15 C-terminal domain-like [142881] (1 protein)
    PfamB 001946

More info for Superfamily d.294.1: EndoU-like

Timeline for Superfamily d.294.1: EndoU-like: