SCOPe 2.08: Protein: Nsp15

Lineage for Protein: Nsp15

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families)
Family c.66.1.48: Nsp15 N-terminal domain-like [142625] (2 proteins)
rudiment methyltransferase fold that probably has lost the enzymatic activity; contains extra N-terminal alpha+beta subdomain
Protein Nsp15 [142626] (2 species)

Species:

Murine hepatitis virus, MHV [TaxId:11138] [142627] (2 PDB entries)
Uniprot P16342 6504-6697! Uniprot P16342 6697-6872
1. Domain for 2gth:
  - Domain d2gtha1: 2gth A:1-194 [135650]
    Other proteins in same PDB: d2gtha2, d2gtha3
2. Domain for 2gti:
  - Domain d2gtia1: 2gti A:1-194 [135652]
    Other proteins in same PDB: d2gtia2, d2gtia3
    complexed with gol, so4; mutant
SARS coronavirus [TaxId:227859] [142628] (3 PDB entries)
Uniprot Q6VA80 6619-6774
1. Domain for 2h85:
  - Domain d2h85a1: 2h85 A:0-190 [136233]
    Other proteins in same PDB: d2h85a2, d2h85a3
2. Domains for 2ozk:
  1. Domain d2ozka1: 2ozk A:27-190 [149107]
    Other proteins in same PDB: d2ozka2, d2ozkb2, d2ozkc2, d2ozkd2
  2. Domain d2ozkb1: 2ozk B:28-190 [149109]
    Other proteins in same PDB: d2ozka2, d2ozkb2, d2ozkc2, d2ozkd2
    automated match to d2ozka1
  3. Domain d2ozkc1: 2ozk C:29-190 [149111]
    Other proteins in same PDB: d2ozka2, d2ozkb2, d2ozkc2, d2ozkd2
    automated match to d2ozka1
  4. Domain d2ozkd1: 2ozk D:29-190 [149113]
    Other proteins in same PDB: d2ozka2, d2ozkb2, d2ozkc2, d2ozkd2
    automated match to d2ozka1
3. Domains for 2rhb:
  1. Domain d2rhba1: 2rhb A:1-190 [152036]
    Other proteins in same PDB: d2rhba2, d2rhba3, d2rhbb2, d2rhbb3, d2rhbc2, d2rhbc3, d2rhbd2, d2rhbd3, d2rhbe2, d2rhbe3, d2rhbf2
    automated match to d2h85a1
    mutant
  2. Domain d2rhbb1: 2rhb B:1-190 [152038]
    Other proteins in same PDB: d2rhba2, d2rhba3, d2rhbb2, d2rhbb3, d2rhbc2, d2rhbc3, d2rhbd2, d2rhbd3, d2rhbe2, d2rhbe3, d2rhbf2
    automated match to d2h85a1
    mutant
  3. Domain d2rhbc1: 2rhb C:1-190 [152040]
    Other proteins in same PDB: d2rhba2, d2rhba3, d2rhbb2, d2rhbb3, d2rhbc2, d2rhbc3, d2rhbd2, d2rhbd3, d2rhbe2, d2rhbe3, d2rhbf2
    automated match to d2h85a1
    mutant
  4. Domain d2rhbd1: 2rhb D:1-190 [152042]
    Other proteins in same PDB: d2rhba2, d2rhba3, d2rhbb2, d2rhbb3, d2rhbc2, d2rhbc3, d2rhbd2, d2rhbd3, d2rhbe2, d2rhbe3, d2rhbf2
    automated match to d2h85a1
    mutant
  5. Domain d2rhbe1: 2rhb E:1-190 [152044]
    Other proteins in same PDB: d2rhba2, d2rhba3, d2rhbb2, d2rhbb3, d2rhbc2, d2rhbc3, d2rhbd2, d2rhbd3, d2rhbe2, d2rhbe3, d2rhbf2
    automated match to d2h85a1
    mutant
  6. Domain d2rhbf1: 2rhb F:1-190 [152046]
    Other proteins in same PDB: d2rhba2, d2rhba3, d2rhbb2, d2rhbb3, d2rhbc2, d2rhbc3, d2rhbd2, d2rhbd3, d2rhbe2, d2rhbe3, d2rhbf2
    automated match to d2h85a1
    mutant

More info for Protein Nsp15 from c.66.1.48: Nsp15 N-terminal domain-like

Timeline for Protein Nsp15 from c.66.1.48: Nsp15 N-terminal domain-like:

Protein Nsp15 from c.66.1.48: Nsp15 N-terminal domain-like first appeared in SCOP 1.73
Protein Nsp15 from c.66.1.48: Nsp15 N-terminal domain-like appears in SCOPe 2.07