SCOPe 2.07: Family c.66.1.48: Nsp15 N-terminal domain-like

Lineage for Family c.66.1.48: Nsp15 N-terminal domain-like

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.48: Nsp15 N-terminal domain-like [142625] (2 proteins)
   rudiment methyltransferase fold that probably has lost the enzymatic activity; contains extra N-terminal alpha+beta subdomain

Proteins:

1. Nsp15 [142626] (2 species)

   1. Species Murine hepatitis virus, MHV [TaxId:11138] [142627] (2 PDB entries)
      Uniprot P16342 6504-6697! Uniprot P16342 6697-6872

   2. Species SARS coronavirus [TaxId:227859] [142628] (3 PDB entries)
      Uniprot Q6VA80 6619-6774

2. automated matches [381979] (2 species)
   not a true protein

   1. Species Sars coronavirus [TaxId:227859] [381980] (1 PDB entry)

   2. Species Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049] [382217] (33 PDB entries)

More info for Family c.66.1.48: Nsp15 N-terminal domain-like

Timeline for Family c.66.1.48: Nsp15 N-terminal domain-like:

• Family c.66.1.48: Nsp15 N-terminal domain-like first appeared in SCOP 1.73
  
• Family c.66.1.48: Nsp15 N-terminal domain-like appears in SCOPe 2.06
  
• Family c.66.1.48: Nsp15 N-terminal domain-like appears in the current release, SCOPe 2.08