Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2887810Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 2889494Superfamily c.56.5: Zn-dependent exopeptidases [53187] (10 families) (S)
    core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
  5. 2889961Family c.56.5.8: Glutaminyl-peptide cyclotransferase-like [142532] (1 protein)
    part of Pfam PF04389
  6. 2889962Protein Glutaminyl-peptide cyclotransferase, QPCT [142533] (2 species)
    Glutaminyl cyclase
  7. 2889963Species Human (Homo sapiens) [TaxId:9606] [142534] (29 PDB entries)
    Uniprot Q16769 33-361

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 2afm:
    1. 2889970Domain d2afma1: 2afm A:33-361 [126698]
      complexed with so4, zn
    2. 2889971Domain d2afmb_: 2afm B: [126699]
      automated match to d2afma1
      complexed with so4, zn
  2. Domain(s) for 2afo:
    1. 2890013Domain d2afoa_: 2afo A: [126700]
      automated match to d2afma1
      complexed with so4, zn
    2. 2890014Domain d2afob_: 2afo B: [126701]
      automated match to d2afma1
      complexed with so4, zn
  3. Domain(s) for 2afs:
    1. 2890006Domain d2afsa1: 2afs A:33-361 [126702]
      complexed with so4, zn; mutant
    2. 2890007Domain d2afsb_: 2afs B: [126703]
      automated match to d2afma1
      complexed with so4, zn; mutant
  4. Domain(s) for 2afu:
    1. 2890004Domain d2afua1: 2afu A:33-361 [126705]
      complexed with bgt, zn
    2. 2890005Domain d2afub_: 2afu B: [126706]
      automated match to d2afma1
      complexed with bgt, zn
  5. Domain(s) for 2afw:
    1. 2889964Domain d2afwa_: 2afw A: [126707]
      automated match to d2afma1
      complexed with ahn, so4, zn
    2. 2889965Domain d2afwb_: 2afw B: [126708]
      automated match to d2afma1
      complexed with ahn, so4, zn
  6. Domain(s) for 2afx:
    1. 2889966Domain d2afxa_: 2afx A: [126709]
      automated match to d2afma1
      complexed with 1bn, so4, zn
    2. 2889967Domain d2afxb_: 2afx B: [126710]
      automated match to d2afma1
      complexed with 1bn, so4, zn
  7. Domain(s) for 2afz:
    1. 2889974Domain d2afza_: 2afz A: [126712]
      automated match to d2afma1
      complexed with nvi, so4, zn
    2. 2889975Domain d2afzb_: 2afz B: [126713]
      automated match to d2afma1
      complexed with nvi, so4, zn
  8. Domain(s) for 2zed:
    1. 2890008Domain d2zeda_: 2zed A: [171173]
      automated match to d2afma1
      complexed with so4, zn; mutant
    2. 2890009Domain d2zedb_: 2zed B: [171174]
      automated match to d2afma1
      complexed with so4, zn; mutant
  9. Domain(s) for 2zee:
    1. 2889989Domain d2zeea_: 2zee A: [171175]
      automated match to d2afma1
      complexed with so4, zn; mutant
    2. 2889990Domain d2zeeb_: 2zee B: [171176]
      automated match to d2afma1
      complexed with so4, zn; mutant
  10. Domain(s) for 2zef:
    1. 2889972Domain d2zefa_: 2zef A: [171177]
      automated match to d2afma1
      complexed with so4, zn; mutant
    2. 2889973Domain d2zefb_: 2zef B: [171178]
      automated match to d2afma1
      complexed with so4, zn; mutant
  11. Domain(s) for 2zeg:
    1. 2889991Domain d2zega_: 2zeg A: [171179]
      automated match to d2afma1
      complexed with imd, so4, zn; mutant
    2. 2889992Domain d2zegb_: 2zeg B: [171180]
      automated match to d2afma1
      complexed with imd, so4, zn; mutant
  12. Domain(s) for 2zeh:
    1. 2889978Domain d2zeha_: 2zeh A: [154403]
      automated match to d2afma1
      complexed with so4, zn; mutant
    2. 2889979Domain d2zehb_: 2zeh B: [154404]
      automated match to d2afma1
      complexed with so4, zn; mutant
  13. Domain(s) for 2zel:
    1. 2889987Domain d2zela_: 2zel A: [171181]
      automated match to d2afma1
      complexed with so4, zn; mutant
    2. 2889988Domain d2zelb_: 2zel B: [171182]
      automated match to d2afma1
      complexed with so4, zn; mutant
  14. Domain(s) for 2zem:
    1. 2890000Domain d2zema_: 2zem A: [171183]
      automated match to d2afma1
      complexed with so4, zn; mutant
    2. 2890001Domain d2zemb_: 2zem B: [171184]
      automated match to d2afma1
      complexed with so4, zn; mutant
  15. Domain(s) for 2zen:
    1. 2889976Domain d2zena_: 2zen A: [171185]
      automated match to d2afma1
      complexed with so4, zn; mutant
    2. 2889977Domain d2zenb_: 2zen B: [171186]
      automated match to d2afma1
      complexed with so4, zn; mutant
  16. Domain(s) for 2zeo:
    1. 2889968Domain d2zeoa_: 2zeo A: [171187]
      automated match to d2afma1
      complexed with so4, zn; mutant
    2. 2889969Domain d2zeob_: 2zeo B: [171188]
      automated match to d2afma1
      complexed with so4, zn; mutant
  17. Domain(s) for 2zep:
    1. 2889995Domain d2zepa_: 2zep A: [171189]
      automated match to d2afma1
      complexed with so4, zn; mutant
    2. 2889996Domain d2zepb_: 2zep B: [171190]
      automated match to d2afma1
      complexed with so4, zn; mutant
  18. Domain(s) for 3pbb:
    1. 2889993Domain d3pbba_: 3pbb A: [183631]
      automated match to d2afma1
      complexed with pbd, zn
    2. 2889994Domain d3pbbb_: 3pbb B: [183632]
      automated match to d2afma1
      complexed with pbd, zn
  19. Domain(s) for 3pbe:
    1. 2889980Domain d3pbea_: 3pbe A: [183634]
      automated match to d2afma1
      complexed with so4, zn; mutant
    2. 2889981Domain d3pbeb_: 3pbe B: [183635]
      automated match to d2afma1
      complexed with so4, zn; mutant
  20. Domain(s) for 3si0:
  21. Domain(s) for 4yu9:
    1. 2890019Domain d4yu9a_: 4yu9 A: [275753]
      automated match to d2zela_
      complexed with edo, so4, zn; mutant
    2. 2890020Domain d4yu9b_: 4yu9 B: [275752]
      automated match to d2zela_
      complexed with edo, so4, zn; mutant
    3. 2890021Domain d4yu9c_: 4yu9 C: [275754]
      automated match to d2zela_
      complexed with edo, so4, zn; mutant
  22. Domain(s) for 4ywy:
    1. 2890016Domain d4ywya_: 4ywy A: [275755]
      automated match to d2zema_
      complexed with cl, edo, pbd, so4, zn; mutant
    2. 2890017Domain d4ywyb_: 4ywy B: [275758]
      automated match to d2zema_
      complexed with cl, edo, pbd, so4, zn; mutant
    3. 2890018Domain d4ywyc_: 4ywy C: [275757]
      automated match to d2zema_
      complexed with cl, edo, pbd, so4, zn; mutant
  23. Domain(s) for 6gbx:
    1. 2890010Domain d6gbxa_: 6gbx A: [357736]
      automated match to d3pbea_
      complexed with edo, s77, so4, zn
    2. 2890011Domain d6gbxb_: 6gbx B: [357742]
      automated match to d3pbea_
      complexed with edo, s77, so4, zn
    3. 2890012Domain d6gbxc_: 6gbx C: [357790]
      automated match to d3pbea_
      complexed with edo, s77, so4, zn
  24. Domain(s) for 6yi1:
    1. 2890002Domain d6yi1a1: 6yi1 A:35-361 [388784]
      Other proteins in same PDB: d6yi1a2, d6yi1b2
      automated match to d2zeha_
      complexed with 66n, dio, gol, mes, ort, peg, pg4, pge, phe, so4, zn
    2. 2890003Domain d6yi1b1: 6yi1 B:35-361 [388826]
      Other proteins in same PDB: d6yi1a2, d6yi1b2
      automated match to d2zeha_
      complexed with 66n, dio, gol, mes, ort, peg, pg4, pge, phe, so4, zn
  25. Domain(s) for 6yjy:
    1. 2889982Domain d6yjya1: 6yjy A:35-361 [388817]
      Other proteins in same PDB: d6yjya2, d6yjyb2
      automated match to d2zeha_
      complexed with gln, leu, mes, pca, so4, tyr, zn
    2. 2889983Domain d6yjyb1: 6yjy B:35-361 [388836]
      Other proteins in same PDB: d6yjya2, d6yjyb2
      automated match to d2zeha_
      complexed with gln, leu, mes, pca, so4, tyr, zn
  26. Domain(s) for 7cm0:
    1. 3084520Domain d7cm0a_: 7cm0 A: [420837]
      automated match to d2zeha_
      complexed with g5r, zn
    2. 3084535Domain d7cm0b_: 7cm0 B: [420852]
      automated match to d2zeha_
      complexed with g5r, zn
    3. 3084547Domain d7cm0c_: 7cm0 C: [420864]
      automated match to d2zeha_
      complexed with g5r, zn
    4. 3084564Domain d7cm0d_: 7cm0 D: [420881]
      automated match to d2zeha_
      complexed with g5r, zn
  27. Domain(s) for 7coz:
    1. 2889997Domain d7coza_: 7coz A: [398687]
      automated match to d4ywya_
      complexed with edo, q39, so4, zn; mutant
    2. 2889998Domain d7cozb_: 7coz B: [398700]
      automated match to d4ywya_
      complexed with edo, q39, so4, zn; mutant
    3. 2889999Domain d7cozc_: 7coz C: [398697]
      automated match to d4ywya_
      complexed with edo, q39, so4, zn; mutant
  28. Domain(s) for 7cp0:
    1. 2889984Domain d7cp0a_: 7cp0 A: [398707]
      automated match to d4ywya_
      complexed with edo, so4, zn; mutant
    2. 2889985Domain d7cp0b_: 7cp0 B: [398714]
      automated match to d4ywya_
      complexed with edo, so4, zn; mutant
    3. 2889986Domain d7cp0c_: 7cp0 C: [398758]
      automated match to d4ywya_
      complexed with edo, so4, zn; mutant
  29. Domain(s) for 7d8e:
    1. 3084780Domain d7d8ea_: 7d8e A: [421097]
      automated match to d3pbea_
      complexed with edo, gyo, so4, zn; mutant
    2. 3084898Domain d7d8ec_: 7d8e C: [421215]
      automated match to d3pbea_
      complexed with edo, gyo, so4, zn; mutant
    3. 3084923Domain d7d8eb_: 7d8e B: [421240]
      automated match to d3pbea_
      complexed with edo, gyo, so4, zn; mutant

More info for Species Human (Homo sapiens) [TaxId:9606] from c.56.5.8 Glutaminyl-peptide cyclotransferase, QPCT

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.56.5.8 Glutaminyl-peptide cyclotransferase, QPCT: