Lineage for Protein: Glutaminyl-peptide cyclotransferase, QPCT

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2464564Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 2466053Superfamily c.56.5: Zn-dependent exopeptidases [53187] (10 families) (S)
    core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
  5. 2466496Family c.56.5.8: Glutaminyl-peptide cyclotransferase-like [142532] (1 protein)
    part of Pfam PF04389
  6. 2466497Protein Glutaminyl-peptide cyclotransferase, QPCT [142533] (2 species)
    Glutaminyl cyclase

Species:

  1. 2466498Human (Homo sapiens) [TaxId:9606] [142534] (23 PDB entries)
    Uniprot Q16769 33-361
    1. Domains for 2afm:
      1. 2466505Domain d2afma1: 2afm A:33-361 [126698]
        complexed with so4, zn
      2. 2466506Domain d2afmb_: 2afm B: [126699]
        automated match to d2afma1
        complexed with so4, zn
    2. Domains for 2afo:
      1. 2466535Domain d2afoa_: 2afo A: [126700]
        automated match to d2afma1
        complexed with so4, zn
      2. 2466536Domain d2afob_: 2afo B: [126701]
        automated match to d2afma1
        complexed with so4, zn
    3. Domains for 2afs:
      1. 2466531Domain d2afsa1: 2afs A:33-361 [126702]
        complexed with so4, zn; mutant
      2. 2466532Domain d2afsb_: 2afs B: [126703]
        automated match to d2afma1
        complexed with so4, zn; mutant
    4. Domains for 2afu:
      1. 2466529Domain d2afua1: 2afu A:33-361 [126705]
        complexed with bgt, zn
      2. 2466530Domain d2afub_: 2afu B: [126706]
        automated match to d2afma1
        complexed with bgt, zn
    5. Domains for 2afw:
      1. 2466499Domain d2afwa_: 2afw A: [126707]
        automated match to d2afma1
        complexed with ahn, so4, zn
      2. 2466500Domain d2afwb_: 2afw B: [126708]
        automated match to d2afma1
        complexed with ahn, so4, zn
    6. Domains for 2afx:
      1. 2466501Domain d2afxa_: 2afx A: [126709]
        automated match to d2afma1
        complexed with 1bn, so4, zn
      2. 2466502Domain d2afxb_: 2afx B: [126710]
        automated match to d2afma1
        complexed with 1bn, so4, zn
    7. Domains for 2afz:
      1. 2466509Domain d2afza_: 2afz A: [126712]
        automated match to d2afma1
        complexed with nvi, so4, zn
      2. 2466510Domain d2afzb_: 2afz B: [126713]
        automated match to d2afma1
        complexed with nvi, so4, zn
    8. Domains for 2zed:
      1. 2466533Domain d2zeda_: 2zed A: [171173]
        automated match to d2afma1
        complexed with so4, zn; mutant
      2. 2466534Domain d2zedb_: 2zed B: [171174]
        automated match to d2afma1
        complexed with so4, zn; mutant
    9. Domains for 2zee:
      1. 2466519Domain d2zeea_: 2zee A: [171175]
        automated match to d2afma1
        complexed with so4, zn; mutant
      2. 2466520Domain d2zeeb_: 2zee B: [171176]
        automated match to d2afma1
        complexed with so4, zn; mutant
    10. Domains for 2zef:
      1. 2466507Domain d2zefa_: 2zef A: [171177]
        automated match to d2afma1
        complexed with so4, zn; mutant
      2. 2466508Domain d2zefb_: 2zef B: [171178]
        automated match to d2afma1
        complexed with so4, zn; mutant
    11. Domains for 2zeg:
      1. 2466521Domain d2zega_: 2zeg A: [171179]
        automated match to d2afma1
        complexed with imd, so4, zn; mutant
      2. 2466522Domain d2zegb_: 2zeg B: [171180]
        automated match to d2afma1
        complexed with imd, so4, zn; mutant
    12. Domains for 2zeh:
      1. 2466513Domain d2zeha_: 2zeh A: [154403]
        automated match to d2afma1
        complexed with so4, zn; mutant
      2. 2466514Domain d2zehb_: 2zeh B: [154404]
        automated match to d2afma1
        complexed with so4, zn; mutant
    13. Domains for 2zel:
      1. 2466517Domain d2zela_: 2zel A: [171181]
        automated match to d2afma1
        complexed with so4, zn; mutant
      2. 2466518Domain d2zelb_: 2zel B: [171182]
        automated match to d2afma1
        complexed with so4, zn; mutant
    14. Domains for 2zem:
      1. 2466527Domain d2zema_: 2zem A: [171183]
        automated match to d2afma1
        complexed with so4, zn; mutant
      2. 2466528Domain d2zemb_: 2zem B: [171184]
        automated match to d2afma1
        complexed with so4, zn; mutant
    15. Domains for 2zen:
      1. 2466511Domain d2zena_: 2zen A: [171185]
        automated match to d2afma1
        complexed with so4, zn; mutant
      2. 2466512Domain d2zenb_: 2zen B: [171186]
        automated match to d2afma1
        complexed with so4, zn; mutant
    16. Domains for 2zeo:
      1. 2466503Domain d2zeoa_: 2zeo A: [171187]
        automated match to d2afma1
        complexed with so4, zn; mutant
      2. 2466504Domain d2zeob_: 2zeo B: [171188]
        automated match to d2afma1
        complexed with so4, zn; mutant
    17. Domains for 2zep:
      1. 2466525Domain d2zepa_: 2zep A: [171189]
        automated match to d2afma1
        complexed with so4, zn; mutant
      2. 2466526Domain d2zepb_: 2zep B: [171190]
        automated match to d2afma1
        complexed with so4, zn; mutant
    18. Domains for 3pbb:
      1. 2466523Domain d3pbba_: 3pbb A: [183631]
        automated match to d2afma1
        complexed with pbd, zn
      2. 2466524Domain d3pbbb_: 3pbb B: [183632]
        automated match to d2afma1
        complexed with pbd, zn
    19. Domains for 3pbe:
      1. 2466515Domain d3pbea_: 3pbe A: [183634]
        automated match to d2afma1
        complexed with so4, zn; mutant
      2. 2466516Domain d3pbeb_: 3pbe B: [183635]
        automated match to d2afma1
        complexed with so4, zn; mutant
    20. Domain for 3si0:
    21. Domains for 4yu9:
      1. 2466540Domain d4yu9a_: 4yu9 A: [275753]
        automated match to d2zela_
        complexed with edo, so4, zn; mutant
      2. 2466541Domain d4yu9b_: 4yu9 B: [275752]
        automated match to d2zela_
        complexed with edo, so4, zn; mutant
      3. 2466542Domain d4yu9c_: 4yu9 C: [275754]
        automated match to d2zela_
        complexed with edo, so4, zn; mutant
    22. Domains for 4ywy:
      1. 2466537Domain d4ywya_: 4ywy A: [275755]
        automated match to d2zema_
        complexed with cl, edo, pbd, so4, zn; mutant
      2. 2466538Domain d4ywyb_: 4ywy B: [275758]
        automated match to d2zema_
        complexed with cl, edo, pbd, so4, zn; mutant
      3. 2466539Domain d4ywyc_: 4ywy C: [275757]
        automated match to d2zema_
        complexed with cl, edo, pbd, so4, zn; mutant
    23. Domains for 6gbx:
      1. 3057674Domain d6gbxa_: 6gbx A: [357736]
        automated match to d3pbea_
        complexed with edo, s77, so4, zn
      2. 3057680Domain d6gbxb_: 6gbx B: [357742]
        automated match to d3pbea_
        complexed with edo, s77, so4, zn
      3. 3057728Domain d6gbxc_: 6gbx C: [357790]
        automated match to d3pbea_
        complexed with edo, s77, so4, zn
  2. 2466544Mouse (Mus musculus) [TaxId:10090] [189699] (2 PDB entries)
    1. Domain for 3si1:
    2. Domain for 3si2:

More info for Protein Glutaminyl-peptide cyclotransferase, QPCT from c.56.5.8: Glutaminyl-peptide cyclotransferase-like

Timeline for Protein Glutaminyl-peptide cyclotransferase, QPCT from c.56.5.8: Glutaminyl-peptide cyclotransferase-like:

  • Protein Glutaminyl-peptide cyclotransferase, QPCT from c.56.5.8: Glutaminyl-peptide cyclotransferase-like first appeared in SCOP 1.73
  • Protein Glutaminyl-peptide cyclotransferase, QPCT from c.56.5.8: Glutaminyl-peptide cyclotransferase-like appears in SCOPe 2.06