Class c: Alpha and beta proteins (a/b) [51349] (147 folds) |
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465 |
Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules |
Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (8 proteins) the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology |
Protein Pyruvate oxidase [88729] (2 species) |
Species Aerococcus viridans [TaxId:1377] [142203] (4 PDB entries) |
Domain d1v5ea2: 1v5e A:3-186 [119845] Other proteins in same PDB: d1v5ea1, d1v5ea3 complexed with fad, so4 |
Domain d1v5fa2: 1v5f A:4-186 [119848] Other proteins in same PDB: d1v5fa1, d1v5fa3 automatically matched to 1V5E A:3-186 complexed with fad, mg, so4, tpp |
Domain d1v5ga2: 1v5g A:4-186 [119851] Other proteins in same PDB: d1v5ga1, d1v5ga3 automatically matched to 1V5E A:3-186 complexed with fad, htl, mg |
Domain d2djia2: 2dji A:3-186 [131545] Other proteins in same PDB: d2djia1, d2djia3 automatically matched to 1V5E A:3-186 complexed with fad, so4 |
Timeline for Species Aerococcus viridans [TaxId:1377] from c.36.1.5 Pyruvate oxidase: