SCOPe 2.01: Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1)

Lineage for Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.108: HAD-like [56783] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.108.1: HAD-like [56784] (26 families)
   usually contains an insertion (sub)domain after strand 1

5. Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1) [142183] (2 proteins)
   Pfam PF05822; the insertion subdomain is a rudiment 4-helical bundle

Proteins:

1. Cytosolic 5'-nucleotidase III [142184] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [142185] (1 PDB entry)
      Uniprot Q9H0P0 64-336

   2. Species Mouse (Mus musculus) [TaxId:10090] [159536] (6 PDB entries)
      Uniprot Q9D020 7-297

2. automated matches [190392] (2 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [187255] (1 PDB entry)

   2. Species Mouse (Mus musculus) [TaxId:10090] [188220] (1 PDB entry)

More info for Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1)

Timeline for Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1):

• Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1) first appeared in SCOP 1.73
  
• Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1) appears in SCOP 1.75
  
• Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1) appears in SCOPe 2.02
  
• Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1) appears in the current release, SCOPe 2.08