Lineage for Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.108: HAD-like [56783] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.108.1: HAD-like [56784] (23 families) usually contains an insertion (sub)domain after strand 1

5. Family c.108.1.21: Pyrimidine 5'-nucleotidase (UMPH-1) [142183] (1 protein) Pfam PF05822; the insertion subdomain is a rudiment 4-helical bundle