Lineage for Species: Streptococcus pyogenes [TaxId: 1314]

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.108: HAD-like [56783] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.108.1: HAD-like [56784] (26 families) usually contains an insertion (sub)domain after strand 1

5. Family c.108.1.14: NagD-like [102317] (7 proteins) duplication: consists of two segment-swapped domains of this fold; this results in the insertion of a circularly permuted domain after strand 3, analogously to the Cof family

6. Protein Hypothetical protein SPy1043 [142167] (1 species)

7. Species Streptococcus pyogenes [TaxId:1314] [142168] (1 PDB entry) Uniprot Q99ZW4 2-254